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Amorphous drug-PVP dispersions: application of theoretical, thermal and spectroscopic analytical techniques to the study of a molecule with intermolecular bonds in both the crystalline and pure amorphous state.
Tobyn M, Brown J, Dennis AB, Fakes M, Gao Q, Gamble J, Khimyak YZ, McGeorge G, Patel C, Sinclair W, Timmins P, Yin S. Tobyn M, et al. Among authors: brown j. J Pharm Sci. 2009 Sep;98(9):3456-68. doi: 10.1002/jps.21738. J Pharm Sci. 2009. PMID: 19603506
A novel co-processing method to manufacture an API for extended release formulation via formation of agglomerates of active ingredient and hydroxypropyl methylcellulose during crystallization.
Rosenbaum T, Erdemir D, Chang SY, Kientzler D, Wang S, Chan SH, Brown J, Hanley S, Kiang S. Rosenbaum T, et al. Among authors: brown j. Drug Dev Ind Pharm. 2018 Oct;44(10):1606-1612. doi: 10.1080/03639045.2018.1483386. Epub 2018 Aug 14. Drug Dev Ind Pharm. 2018. PMID: 29916275
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