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SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy.
Drilon A, Sharma MR, Johnson ML, Yap TA, Gadgeel S, Nepert D, Feng G, Reddy MB, Harney AS, Elsayed M, Cook AW, Wong CE, Hinklin RJ, Jiang Y, Brown EN, Neitzel NA, Laird ER, Wu WI, Singh A, Wei P, Ching KA, Gaudino JJ, Lee PA, Hartley DP, Rothenberg SM. Drilon A, et al. Among authors: brown en. Cancer Discov. 2023 Aug 4;13(8):1789-1801. doi: 10.1158/2159-8290.CD-23-0361. Cancer Discov. 2023. PMID: 37269335 Free PMC article.
A next-generation BRAF inhibitor overcomes resistance to BRAF inhibition in patients with BRAF-mutant cancers using pharmacokinetics-informed dose escalation.
Yaeger R, McKean MA, Haq R, Beck JT, Taylor MH, Cohen JE, Bowles DW, Gadgeel SM, Mihalcioiu C, Papadopoulos KP, Diamond EL, Sturtz KB, Feng G, Drescher SK, Reddy MB, Sengupta B, Maity AK, Brown SA, Singh A, Brown EN, Baer BR, Wong J, Mou TC, Wu WI, Kahn DR, Gadal S, Rosen N, Gaudino JJ, Lee PA, Hartley DP, Rothenberg SM. Yaeger R, et al. Among authors: brown en. Cancer Discov. 2024 Apr 30. doi: 10.1158/2159-8290.CD-24-0024. Online ahead of print. Cancer Discov. 2024. PMID: 38691346
Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness.
Edlow BL, Olchanyi M, Freeman HJ, Li J, Maffei C, Snider SB, Zöllei L, Iglesias JE, Augustinack J, Bodien YG, Haynes RL, Greve DN, Diamond BR, Stevens A, Giacino JT, Destrieux C, van der Kouwe A, Brown EN, Folkerth RD, Fischl B, Kinney HC. Edlow BL, et al. Among authors: brown en. Sci Transl Med. 2024 May;16(745):eadj4303. doi: 10.1126/scitranslmed.adj4303. Epub 2024 May 1. Sci Transl Med. 2024. PMID: 38691619
Closed-loop control of anesthetic state in nonhuman primates.
Chakravarty S, Donoghue J, Waite AS, Mahnke M, Garwood IC, Gallo S, Miller EK, Brown EN. Chakravarty S, et al. Among authors: brown en. PNAS Nexus. 2023 Oct 31;2(10):pgad293. doi: 10.1093/pnasnexus/pgad293. eCollection 2023 Oct. PNAS Nexus. 2023. PMID: 37920551 Free PMC article.
438 results