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Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.
Hazenbos WL, Kajihara KK, Vandlen R, Morisaki JH, Lehar SM, Kwakkenbos MJ, Beaumont T, Bakker AQ, Phung Q, Swem LR, Ramakrishnan S, Kim J, Xu M, Shah IM, Diep BA, Sai T, Sebrell A, Khalfin Y, Oh A, Koth C, Lin SJ, Lee BC, Strandh M, Koefoed K, Andersen PS, Spits H, Brown EJ, Tan MW, Mariathasan S. Hazenbos WL, et al. Among authors: brown ej. PLoS Pathog. 2013;9(10):e1003653. doi: 10.1371/journal.ppat.1003653. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130480 Free PMC article. Clinical Trial.
Novel antibody-antibiotic conjugate eliminates intracellular S. aureus.
Lehar SM, Pillow T, Xu M, Staben L, Kajihara KK, Vandlen R, DePalatis L, Raab H, Hazenbos WL, Morisaki JH, Kim J, Park S, Darwish M, Lee BC, Hernandez H, Loyet KM, Lupardus P, Fong R, Yan D, Chalouni C, Luis E, Khalfin Y, Plise E, Cheong J, Lyssikatos JP, Strandh M, Koefoed K, Andersen PS, Flygare JA, Wah Tan M, Brown EJ, Mariathasan S. Lehar SM, et al. Among authors: brown ej. Nature. 2015 Nov 19;527(7578):323-8. doi: 10.1038/nature16057. Epub 2015 Nov 4. Nature. 2015. PMID: 26536114
A Putative Bacterial ABC Transporter Circumvents the Essentiality of Signal Peptidase.
Morisaki JH, Smith PA, Date SV, Kajihara KK, Truong CL, Modrusan Z, Yan D, Kang J, Xu M, Shah IM, Mintzer R, Kofoed EM, Cheung TK, Arnott D, Koehler MF, Heise CE, Brown EJ, Tan MW, Hazenbos WL. Morisaki JH, et al. Among authors: brown ej. mBio. 2016 Sep 6;7(5):e00412-16. doi: 10.1128/mBio.00412-16. mBio. 2016. PMID: 27601569 Free PMC article.
Host-derived fatty acids activate type VII secretion in Staphylococcus aureus.
Lopez MS, Tan IS, Yan D, Kang J, McCreary M, Modrusan Z, Austin CD, Xu M, Brown EJ. Lopez MS, et al. Among authors: brown ej. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11223-11228. doi: 10.1073/pnas.1700627114. Epub 2017 Oct 2. Proc Natl Acad Sci U S A. 2017. PMID: 28973946 Free PMC article.
518 results