Brown CJ - Search Results

1

De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits.

Ng S, Juang YC, Chandramohan A, Kaan HYK, Sadruddin A, Yuen TY, Ferrer-Gago FJ, Lee XC, Liew X, Johannes CW, Brown CJ, Kannan S, Aronica PG, Berglund NA, Verma CS, Liu L, Stoeck A, Sawyer TK, Partridge AW, Lane DP. Ng S, et al. Among authors: brown cj. ACS Med Chem Lett. 2020 May 1;11(10):1993-2001. doi: 10.1021/acsmedchemlett.0c00022. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062184 Free PMC article.

2

The electrostatic surface of MDM2 modulates the specificity of its interaction with phosphorylated and unphosphorylated p53 peptides.

Brown CJ, Srinivasan D, Jun LH, Coomber D, Verma CS, Lane DP. Brown CJ, et al. Cell Cycle. 2008 Mar 1;7(5):608-10. doi: 10.4161/cc.7.5.5488. Epub 2007 Dec 26. Cell Cycle. 2008. PMID: 18256546

3

Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site.

Brown CJ, Verma CS, Walkinshaw MD, Lane DP. Brown CJ, et al. Cell Cycle. 2009 Jun 15;8(12):1905-11. doi: 10.4161/cc.8.12.8742. Epub 2009 Jun 15. Cell Cycle. 2009. PMID: 19440045

4

Design of a novel MDM2 binding peptide based on the p53 family.

Madhumalar A, Lee HJ, Brown CJ, Lane D, Verma C. Madhumalar A, et al. Among authors: brown cj. Cell Cycle. 2009 Sep 1;8(17):2828-36. doi: 10.4161/cc.8.17.9516. Epub 2009 Sep 14. Cell Cycle. 2009. PMID: 19713735

5

Rational design and biophysical characterization of thioredoxin-based aptamers: insights into peptide grafting.

Brown CJ, Dastidar SG, See HY, Coomber DW, Ortiz-Lombardía M, Verma C, Lane DP. Brown CJ, et al. J Mol Biol. 2010 Jan 29;395(4):871-83. doi: 10.1016/j.jmb.2009.10.069. Epub 2009 Nov 3. J Mol Biol. 2010. PMID: 19895821

6

Differential scanning fluorimetry as secondary screening platform for small molecule inhibitors of Bcl-XL.

Wan KF, Wang S, Brown CJ, Yu VC, Entzeroth M, Lane DP, Lee MA. Wan KF, et al. Among authors: brown cj. Cell Cycle. 2009 Dec;8(23):3943-52. doi: 10.4161/cc.8.23.10114. Epub 2009 Dec 17. Cell Cycle. 2009. PMID: 19901550

7

Awakening guardian angels: drugging the p53 pathway.

Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP. Brown CJ, et al. Nat Rev Cancer. 2009 Dec;9(12):862-73. doi: 10.1038/nrc2763. Nat Rev Cancer. 2009. PMID: 19935675 Review.

8

Mdm2 and p53 are highly conserved from placozoans to man.

Lane DP, Cheok CF, Brown C, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Cell Cycle. 2010 Feb 1;9(3):540-7. doi: 10.4161/cc.9.3.10516. Cell Cycle. 2010. PMID: 20081368

9

The Mdm2 and p53 genes are conserved in the Arachnids.

Lane DP, Cheok CF, Brown CJ, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Among authors: brown cj. Cell Cycle. 2010 Feb 15;9(4):748-54. doi: 10.4161/cc.9.4.10616. Epub 2010 Feb 12. Cell Cycle. 2010. PMID: 20160485

10

Differential binding of p53 and nutlin to MDM2 and MDMX: computational studies.

Joseph TL, Madhumalar A, Brown CJ, Lane DP, Verma CS. Joseph TL, et al. Among authors: brown cj. Cell Cycle. 2010 Mar 15;9(6):1167-81. doi: 10.4161/cc.9.6.11067. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20190571

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

940 results

Search Page