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Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex.
Gerrits E, Giannini LAA, Brouwer N, Melhem S, Seilhean D, Le Ber I; Brainbank Neuro-CEB Neuropathology Network; Kamermans A, Kooij G, de Vries HE, Boddeke EWGM, Seelaar H, van Swieten JC, Eggen BJL. Gerrits E, et al. Among authors: brouwer n. Nat Neurosci. 2022 Aug;25(8):1034-1048. doi: 10.1038/s41593-022-01124-3. Epub 2022 Jul 25. Nat Neurosci. 2022. PMID: 35879464
Priming of microglia in a DNA-repair deficient model of accelerated aging.
Raj DD, Jaarsma D, Holtman IR, Olah M, Ferreira FM, Schaafsma W, Brouwer N, Meijer MM, de Waard MC, van der Pluijm I, Brandt R, Kreft KL, Laman JD, de Haan G, Biber KP, Hoeijmakers JH, Eggen BJ, Boddeke HW. Raj DD, et al. Among authors: brouwer n. Neurobiol Aging. 2014 Sep;35(9):2147-60. doi: 10.1016/j.neurobiolaging.2014.03.025. Epub 2014 Mar 28. Neurobiol Aging. 2014. PMID: 24799273 Free article.
Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing.
Schaafsma W, Zhang X, van Zomeren KC, Jacobs S, Georgieva PB, Wolf SA, Kettenmann H, Janova H, Saiepour N, Hanisch UK, Meerlo P, van den Elsen PJ, Brouwer N, Boddeke HW, Eggen BJ. Schaafsma W, et al. Among authors: brouwer n. Brain Behav Immun. 2015 Aug;48:205-21. doi: 10.1016/j.bbi.2015.03.013. Epub 2015 Apr 2. Brain Behav Immun. 2015. PMID: 25843371
149 results