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Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarró LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M. Broutier L, et al. Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13. Nat Med. 2017. PMID: 29131160 Free PMC article.
DCC constrains tumour progression via its dependence receptor activity.
Castets M, Broutier L, Molin Y, Brevet M, Chazot G, Gadot N, Paquet A, Mazelin L, Jarrosson-Wuilleme L, Scoazec JY, Bernet A, Mehlen P. Castets M, et al. Among authors: broutier l. Nature. 2011 Dec 11;482(7386):534-7. doi: 10.1038/nature10708. Nature. 2011. PMID: 22158121
Targeting netrin-1/DCC interaction in diffuse large B-cell and mantle cell lymphomas.
Broutier L, Creveaux M, Vial J, Tortereau A, Delcros JG, Chazot G, McCarron MJ, Léon S, Pangault C, Gadot N, Colombe A, Boulland ML, Blachier J, Marie JC, Traverse-Glehen A, Donzé O, Chassagne-Clément C, Salles G, Tarte K, Mehlen P, Castets M. Broutier L, et al. EMBO Mol Med. 2016 Feb 1;8(2):96-104. doi: 10.15252/emmm.201505480. EMBO Mol Med. 2016. PMID: 26882243 Free PMC article.
Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4.
Royet A, Broutier L, Coissieux MM, Malleval C, Gadot N, Maillet D, Gratadou-Hupon L, Bernet A, Nony P, Treilleux I, Honnorat J, Liebl D, Pelletier L, Berger F, Meyronet D, Castets M, Mehlen P. Royet A, et al. Among authors: broutier l. Oncotarget. 2017 Apr 4;8(14):23750-23759. doi: 10.18632/oncotarget.16077. Oncotarget. 2017. PMID: 28423606 Free PMC article.
[DCC, come back of a suppressor gene in colorectal cancer].
Broutier L, Castets M. Broutier L, et al. Med Sci (Paris). 2012 May;28(5):465-8. doi: 10.1051/medsci/2012285007. Epub 2012 May 30. Med Sci (Paris). 2012. PMID: 22642996 Free article. French. No abstract available.
Schwann cells support oncogenic potential of pancreatic cancer cells through TGFβ signaling.
Roger E, Martel S, Bertrand-Chapel A, Depollier A, Chuvin N, Pommier RM, Yacoub K, Caligaris C, Cardot-Ruffino V, Chauvet V, Aires S, Mohkam K, Mabrut JY, Adham M, Fenouil T, Hervieu V, Broutier L, Castets M, Neuzillet C, Cassier PA, Tomasini R, Sentis S, Bartholin L. Roger E, et al. Among authors: broutier l. Cell Death Dis. 2019 Nov 25;10(12):886. doi: 10.1038/s41419-019-2116-x. Cell Death Dis. 2019. PMID: 31767842 Free PMC article.
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