Broussy S - Search Results

1

Recent advances of anti-angiogenic inhibitors targeting VEGF/VEGFR axis.

Wang L, Liu WQ, Broussy S, Han B, Fang H. Wang L, et al. Among authors: broussy s. Front Pharmacol. 2024 Jan 4;14:1307860. doi: 10.3389/fphar.2023.1307860. eCollection 2023. Front Pharmacol. 2024. PMID: 38239196 Free PMC article. Review.

2

Dimer Peptide Ligands of Vascular Endothelial Growth Factor: Optimizing Linker Length for High Affinity and Antiangiogenic Activity.

Ye X, Gaucher JF, Hu H, Wang L, Broussy S. Ye X, et al. Among authors: broussy s. J Med Chem. 2023 Jul 27;66(14):9753-9765. doi: 10.1021/acs.jmedchem.3c00561. Epub 2023 Jul 6. J Med Chem. 2023. PMID: 37409957

3

A VEGFB-Based Peptidomimetic Inhibits VEGFR2-Mediated PI3K/Akt/mTOR and PLCγ/ERK Signaling and Elicits Apoptotic, Antiangiogenic, and Antitumor Activities.

Namjoo M, Ghafouri H, Assareh E, Aref AR, Mostafavi E, Hamrahi Mohsen A, Balalaie S, Broussy S, Asghari SM. Namjoo M, et al. Among authors: broussy s. Pharmaceuticals (Basel). 2023 Jun 20;16(6):906. doi: 10.3390/ph16060906. Pharmaceuticals (Basel). 2023. PMID: 37375853 Free PMC article.

4

Editorial: Computer-aided drug design: Drug discovery, computational modelling, and artificial intelligence.

Ye F, Lin M, Jin J, Broussy S. Ye F, et al. Among authors: broussy s. Front Chem. 2022 Jul 18;10:968687. doi: 10.3389/fchem.2022.968687. eCollection 2022. Front Chem. 2022. PMID: 35928213 Free PMC article. No abstract available.

5

Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.

Gaucher JF, Reille-Seroussi M, Broussy S. Gaucher JF, et al. Among authors: broussy s. Chemistry. 2022 Aug 26;28(48):e202200465. doi: 10.1002/chem.202200465. Epub 2022 Jul 7. Chemistry. 2022. PMID: 35665969 Free PMC article.

6

A Structural Overview of Vascular Endothelial Growth Factors Pharmacological Ligands: From Macromolecules to Designed Peptidomimetics.

Ye X, Gaucher JF, Vidal M, Broussy S. Ye X, et al. Among authors: broussy s. Molecules. 2021 Nov 9;26(22):6759. doi: 10.3390/molecules26226759. Molecules. 2021. PMID: 34833851 Free PMC article. Review.

7

A Cyclic Peptide Epitope of an Under-Explored VEGF-B Loop 1 Demonstrated In Vivo Anti-Angiogenic and Anti-Tumor Activities.

Wang L, Xu M, Hu H, Zhang L, Ye F, Jin J, Fang H, Chen J, Chen G, Broussy S, Vidal M, Lv Z, Liu WQ. Wang L, et al. Among authors: broussy s. Front Pharmacol. 2021 Sep 29;12:734544. doi: 10.3389/fphar.2021.734544. eCollection 2021. Front Pharmacol. 2021. PMID: 34658874 Free PMC article.

8

Rapid Enantioselective and Diastereoconvergent Hybrid Organic/Biocatalytic Entry into the Oseltamivir Core.

Tiwari VK, Powell DR, Broussy S, Berkowitz DB. Tiwari VK, et al. Among authors: broussy s. J Org Chem. 2021 May 7;86(9):6494-6503. doi: 10.1021/acs.joc.1c00326. Epub 2021 Apr 15. J Org Chem. 2021. PMID: 33857378 Free article.

9

Synthesis of indole inhibitors of silent information regulator 1 (SIRT1), and their evaluation as cytotoxic agents.

Laaroussi H, Ding Y, Teng Y, Deschamps P, Vidal M, Yu P, Broussy S. Laaroussi H, et al. Among authors: broussy s. Eur J Med Chem. 2020 Sep 15;202:112561. doi: 10.1016/j.ejmech.2020.112561. Epub 2020 Jul 2. Eur J Med Chem. 2020. PMID: 32711231

10

Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the Vascular Endothelial Growth Factor Receptor 1 (VEGFR1D2) for anticancer application.

Sadremomtaz A, Ali AM, Jouyandeh F, Balalaie S, Navari R, Broussy S, Mansouri K, Groves MR, Asghari SM. Sadremomtaz A, et al. Among authors: broussy s. Signal Transduct Target Ther. 2020 Jun 5;5(1):76. doi: 10.1038/s41392-020-0177-z. Signal Transduct Target Ther. 2020. PMID: 32499505 Free PMC article. No abstract available.

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