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Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell Lines.
Hum Gene Ther Methods. 2017 Dec;28(6):330-339. doi: 10.1089/hgtb.2017.086. Epub 2017 Nov 21.
Hum Gene Ther Methods. 2017.
PMID: 28826344
Free PMC article.
Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture.
Broussau S, Jabbour N, Lachapelle G, Durocher Y, Tom R, Transfiguracion J, Gilbert R, Massie B.
Broussau S, et al.
Mol Ther. 2008 Mar;16(3):500-7. doi: 10.1038/sj.mt.6300383. Epub 2008 Jan 8.
Mol Ther. 2008.
PMID: 18180776
Free article.
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High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch.
Gaillet B, Gilbert R, Broussau S, Pilotte A, Malenfant F, Mullick A, Garnier A, Massie B.
Gaillet B, et al. Among authors: broussau s.
Biotechnol Bioeng. 2010 Jun 1;106(2):203-15. doi: 10.1002/bit.22698.
Biotechnol Bioeng. 2010.
PMID: 20178120
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Strength and muscle specificity of a compact promoter derived from the slow troponin I gene in the context of episomal (gutless adenovirus) and integrating (lentiviral) vectors.
Robert MA, Lin Y, Bendjelloul M, Zeng Y, Dessolin S, Broussau S, Larochelle N, Nalbantoglu J, Massie B, Gilbert R.
Robert MA, et al. Among authors: broussau s.
J Gene Med. 2012 Dec;14(12):746-60. doi: 10.1002/jgm.2675.
J Gene Med. 2012.
PMID: 23071006
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Culture media selection and feeding strategy for high titer production of a lentiviral vector by stable producer clones cultivated at high cell density.
Shen CF, Tremblay S, Sabourin-Poirier C, Burney E, Broussau S, Manceur A, Rodenbrock A, Voyer R, Loignon M, Ansorge S, Gilbert R.
Shen CF, et al. Among authors: broussau s.
Bioprocess Biosyst Eng. 2022 Aug;45(8):1267-1280. doi: 10.1007/s00449-022-02737-5. Epub 2022 Jun 27.
Bioprocess Biosyst Eng. 2022.
PMID: 35758994
Free PMC article.
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Packaging cells for lentiviral vectors generated using the cumate and coumermycin gene induction systems and nanowell single-cell cloning.
Broussau S, Lytvyn V, Simoneau M, Guilbault C, Leclerc M, Nazemi-Moghaddam N, Coulombe N, Elahi SM, McComb S, Gilbert R.
Broussau S, et al.
Mol Ther Methods Clin Dev. 2023 Feb 26;29:40-57. doi: 10.1016/j.omtm.2023.02.013. eCollection 2023 Jun 8.
Mol Ther Methods Clin Dev. 2023.
PMID: 36936448
Free PMC article.
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The cumate gene-switch: a system for regulated expression in mammalian cells.
Mullick A, Xu Y, Warren R, Koutroumanis M, Guilbault C, Broussau S, Malenfant F, Bourget L, Lamoureux L, Lo R, Caron AW, Pilotte A, Massie B.
Mullick A, et al. Among authors: broussau s.
BMC Biotechnol. 2006 Nov 3;6:43. doi: 10.1186/1472-6750-6-43.
BMC Biotechnol. 2006.
PMID: 17083727
Free PMC article.
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