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AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.
Lepropre S, Kautbally S, Octave M, Ginion A, Onselaer MB, Steinberg GR, Kemp BE, Hego A, Wéra O, Brouns S, Swieringa F, Giera M, Darley-Usmar VM, Ambroise J, Guigas B, Heemskerk J, Bertrand L, Oury C, Beauloye C, Horman S. Lepropre S, et al. Blood. 2018 Sep 13;132(11):1180-1192. doi: 10.1182/blood-2018-02-831503. Epub 2018 Jul 17. Blood. 2018. PMID: 30018077 Free PMC article.
High-throughput elucidation of thrombus formation reveals sources of platelet function variability.
van Geffen JP, Brouns SLN, Batista J, McKinney H, Kempster C, Nagy M, Sivapalaratnam S, Baaten CCFMJ, Bourry N, Frontini M, Jurk K, Krause M, Pillitteri D, Swieringa F, Verdoold R, Cavill R, Kuijpers MJE, Ouwehand WH, Downes K, Heemskerk JWM. van Geffen JP, et al. Haematologica. 2019 Jun;104(6):1256-1267. doi: 10.3324/haematol.2018.198853. Epub 2018 Dec 13. Haematologica. 2019. PMID: 30545925 Free PMC article.
Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases.
Kiran Gotru S, van Geffen JP, Nagy M, Mammadova-Bach E, Eilenberger J, Volz J, Manukjan G, Schulze H, Wagner L, Eber S, Schambeck C, Deppermann C, Brouns S, Nurden P, Greinacher A, Sachs U, Nieswandt B, Hermanns HM, Heemskerk JWM, Braun A. Kiran Gotru S, et al. Sci Rep. 2019 Jun 6;9(1):8333. doi: 10.1038/s41598-019-44751-w. Sci Rep. 2019. PMID: 31171812 Free PMC article.
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism.
Shi C, Kim T, Steiger S, Mulay SR, Klinkhammer BM, Bäuerle T, Melica ME, Romagnani P, Möckel D, Baues M, Yang L, Brouns SLN, Heemskerk JWM, Braun A, Lammers T, Boor P, Anders HJ. Shi C, et al. Circ Res. 2020 Apr 10;126(8):e37-e52. doi: 10.1161/CIRCRESAHA.119.315625. Epub 2020 Feb 24. Circ Res. 2020. PMID: 32089086 Free article.
Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation.
Brouns SLN, van Geffen JP, Campello E, Swieringa F, Spiezia L, van Oerle R, Provenzale I, Verdoold R, Farndale RW, Clemetson KJ, Spronk HMH, van der Meijden PEJ, Cavill R, Kuijpers MJE, Castoldi E, Simioni P, Heemskerk JWM. Brouns SLN, et al. Sci Rep. 2020 Jul 17;10(1):11910. doi: 10.1038/s41598-020-68438-9. Sci Rep. 2020. PMID: 32680988 Free PMC article.
23 results