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Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.
Borrell-Pagès M, Canals JM, Cordelières FP, Parker JA, Pineda JR, Grange G, Bryson EA, Guillermier M, Hirsch E, Hantraye P, Cheetham ME, Néri C, Alberch J, Brouillet E, Saudou F, Humbert S. Borrell-Pagès M, et al. Among authors: brouillet e. J Clin Invest. 2006 May;116(5):1410-24. doi: 10.1172/JCI27607. Epub 2006 Apr 6. J Clin Invest. 2006. PMID: 16604191 Free PMC article.
The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Ben Haim L, Ceyzériat K, Carrillo-de Sauvage MA, Aubry F, Auregan G, Guillermier M, Ruiz M, Petit F, Houitte D, Faivre E, Vandesquille M, Aron-Badin R, Dhenain M, Déglon N, Hantraye P, Brouillet E, Bonvento G, Escartin C. Ben Haim L, et al. Among authors: brouillet e. J Neurosci. 2015 Feb 11;35(6):2817-29. doi: 10.1523/JNEUROSCI.3516-14.2015. J Neurosci. 2015. PMID: 25673868 Free PMC article.
Contribution of Neuroepigenetics to Huntington's Disease.
Francelle L, Lotz C, Outeiro T, Brouillet E, Merienne K. Francelle L, et al. Among authors: brouillet e. Front Hum Neurosci. 2017 Jan 30;11:17. doi: 10.3389/fnhum.2017.00017. eCollection 2017. Front Hum Neurosci. 2017. PMID: 28194101 Free PMC article. Review.
SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2.
Niewiadomska-Cimicka A, Doussau F, Perot JB, Roux MJ, Keime C, Hache A, Piguet F, Novati A, Weber C, Yalcin B, Meziane H, Champy MF, Grandgirard E, Karam A, Messaddeq N, Eisenmann A, Brouillet E, Nguyen HHP, Flament J, Isope P, Trottier Y. Niewiadomska-Cimicka A, et al. Among authors: brouillet e. J Neurosci. 2021 Jun 2;41(22):4910-4936. doi: 10.1523/JNEUROSCI.1882-20.2021. Epub 2021 Apr 22. J Neurosci. 2021. PMID: 33888607 Free PMC article.
161 results