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SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2.
Niewiadomska-Cimicka A, Doussau F, Perot JB, Roux MJ, Keime C, Hache A, Piguet F, Novati A, Weber C, Yalcin B, Meziane H, Champy MF, Grandgirard E, Karam A, Messaddeq N, Eisenmann A, Brouillet E, Nguyen HHP, Flament J, Isope P, Trottier Y. Niewiadomska-Cimicka A, et al. Among authors: brouillet e. J Neurosci. 2021 Jun 2;41(22):4910-4936. doi: 10.1523/JNEUROSCI.1882-20.2021. Epub 2021 Apr 22. J Neurosci. 2021. PMID: 33888607 Free PMC article.
Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo.
Escartin C, Brouillet E, Gubellini P, Trioulier Y, Jacquard C, Smadja C, Knott GW, Kerkerian-Le Goff L, Déglon N, Hantraye P, Bonvento G. Escartin C, et al. Among authors: brouillet e. J Neurosci. 2006 May 31;26(22):5978-89. doi: 10.1523/JNEUROSCI.0302-06.2006. J Neurosci. 2006. PMID: 16738240 Free PMC article.
The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Ben Haim L, Ceyzériat K, Carrillo-de Sauvage MA, Aubry F, Auregan G, Guillermier M, Ruiz M, Petit F, Houitte D, Faivre E, Vandesquille M, Aron-Badin R, Dhenain M, Déglon N, Hantraye P, Brouillet E, Bonvento G, Escartin C. Ben Haim L, et al. Among authors: brouillet e. J Neurosci. 2015 Feb 11;35(6):2817-29. doi: 10.1523/JNEUROSCI.3516-14.2015. J Neurosci. 2015. PMID: 25673868 Free PMC article.
The neuroprotective agent CNTF decreases neuronal metabolites in the rat striatum: an in vivo multimodal magnetic resonance imaging study.
Carrillo-de Sauvage MA, Flament J, Bramoulle Y, Ben Haim L, Guillermier M, Berniard A, Aurégan G, Houitte D, Brouillet E, Bonvento G, Hantraye P, Valette J, Escartin C. Carrillo-de Sauvage MA, et al. Among authors: brouillet e. J Cereb Blood Flow Metab. 2015 Jun;35(6):917-21. doi: 10.1038/jcbfm.2015.48. Epub 2015 Apr 1. J Cereb Blood Flow Metab. 2015. PMID: 25833344 Free PMC article.
Energy defects in Huntington's disease: Why "in vivo" evidence matters.
Liot G, Valette J, Pépin J, Flament J, Brouillet E. Liot G, et al. Among authors: brouillet e. Biochem Biophys Res Commun. 2017 Feb 19;483(4):1084-1095. doi: 10.1016/j.bbrc.2016.09.065. Epub 2016 Sep 14. Biochem Biophys Res Commun. 2017. PMID: 27639641 Review.
161 results