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Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Kan WL, Dhagat U, Kaufmann KB, Hercus TR, Nero TL, Zeng AGX, Toubia J, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheung Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D'Andrea RJ, Dick JE, Parker MW, Lopez AF. Kan WL, et al. Among authors: broughton se. Cancer Discov. 2023 Aug 4;13(8):1922-1947. doi: 10.1158/2159-8290.CD-22-1396. Cancer Discov. 2023. PMID: 37191437 Free PMC article.
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.
Broughton SE, Hercus TR, Nero TL, Kan WL, Barry EF, Dottore M, Cheung Tung Shing KS, Morton CJ, Dhagat U, Hardy MP, Wilson NJ, Downton MT, Schieber C, Hughes TP, Lopez AF, Parker MW. Broughton SE, et al. Nat Commun. 2018 Jan 26;9(1):386. doi: 10.1038/s41467-017-02633-7. Nat Commun. 2018. PMID: 29374162 Free PMC article.
Role of the β Common (βc) Family of Cytokines in Health and Disease.
Hercus TR, Kan WLT, Broughton SE, Tvorogov D, Ramshaw HS, Sandow JJ, Nero TL, Dhagat U, Thompson EJ, Shing KSCT, McKenzie DR, Wilson NJ, Owczarek CM, Vairo G, Nash AD, Tergaonkar V, Hughes T, Ekert PG, Samuel MS, Bonder CS, Grimbaldeston MA, Parker MW, Lopez AF. Hercus TR, et al. Among authors: broughton se. Cold Spring Harb Perspect Biol. 2018 Jun 1;10(6):a028514. doi: 10.1101/cshperspect.a028514. Cold Spring Harb Perspect Biol. 2018. PMID: 28716883 Free PMC article. Review.
Unexpected mechanisms of action for a cytokine receptor-blocking antibody.
Hercus TR, Broughton SE, Hardy MP, Nero TL, Wilson NJ, Parker MW, Lopez AF. Hercus TR, et al. Among authors: broughton se. Mol Cell Oncol. 2014 Dec 31;1(4):e969129. doi: 10.4161/23288604.2014.969129. eCollection 2014 Oct-Dec. Mol Cell Oncol. 2014. PMID: 27308368 Free PMC article.
20 results