Brough D - Search Results

1

Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation.

Kodji X, Kee Z, McKenna R, de Sousa Valente J, Ravenscroft H, McMillan H, Gamble J, Dombrowski Y, Moynagh P, Brough D, Lundy FT, Brain SD, El Karim IA. Kodji X, et al. Among authors: brough d. Pharmaceuticals (Basel). 2021 Oct 23;14(11):1073. doi: 10.3390/ph14111073. Pharmaceuticals (Basel). 2021. PMID: 34832855 Free PMC article.

2

Inhibiting the NLRP3 Inflammasome.

El-Sharkawy LY, Brough D, Freeman S. El-Sharkawy LY, et al. Among authors: brough d. Molecules. 2020 Nov 25;25(23):5533. doi: 10.3390/molecules25235533. Molecules. 2020. PMID: 33255820 Free PMC article. Review.

3

Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome.

Lemarchand E, Barrington J, Chenery A, Haley M, Coutts G, Allen JE, Allan SM, Brough D. Lemarchand E, et al. Among authors: brough d. Stroke. 2019 May;50(5):1232-1239. doi: 10.1161/STROKEAHA.118.023620. Stroke. 2019. PMID: 31009361 Free PMC article.

4

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung.

Chenery AL, Alhallaf R, Agha Z, Ajendra J, Parkinson JE, Cooper MM, Chan BHK, Eichenberger RM, Dent LA, Robertson AAB, Kupz A, Brough D, Loukas A, Sutherland TE, Allen JE, Giacomin PR. Chenery AL, et al. Among authors: brough d. J Immunol. 2019 Nov 15;203(10):2724-2734. doi: 10.4049/jimmunol.1900640. Epub 2019 Oct 4. J Immunol. 2019. PMID: 31586037 Free PMC article.

5

Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture.

Hoyle C, Redondo-Castro E, Cook J, Tzeng TC, Allan SM, Brough D, Lemarchand E. Hoyle C, et al. Among authors: brough d. Immunology. 2020 Sep;161(1):39-52. doi: 10.1111/imm.13221. Epub 2020 Jun 22. Immunology. 2020. PMID: 32445196 Free PMC article.

6

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.

Nizami S, Arunasalam K, Green J, Cook J, Lawrence CB, Zarganes-Tzitzikas T, Davis JB, Di Daniel E, Brough D. Nizami S, et al. Among authors: brough d. Immunology. 2021 Jan;162(1):84-91. doi: 10.1111/imm.13267. Epub 2020 Oct 30. Immunology. 2021. PMID: 32954500 Free PMC article.

7

The NLRP3-inflammasome as a sensor of organelle dysfunction.

Seoane PI, Lee B, Hoyle C, Yu S, Lopez-Castejon G, Lowe M, Brough D. Seoane PI, et al. Among authors: brough d. J Cell Biol. 2020 Dec 7;219(12):e202006194. doi: 10.1083/jcb.202006194. J Cell Biol. 2020. PMID: 33044555 Free PMC article. Review.

8

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro.

Gritsenko A, Yu S, Martin-Sanchez F, Diaz-Del-Olmo I, Nichols EM, Davis DM, Brough D, Lopez-Castejon G. Gritsenko A, et al. Among authors: brough d. Front Immunol. 2020 Sep 30;11:565924. doi: 10.3389/fimmu.2020.565924. eCollection 2020. Front Immunol. 2020. PMID: 33101286 Free PMC article.

9

Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification.

Yu S, Green J, Wellens R, Lopez-Castejon G, Brough D. Yu S, et al. Among authors: brough d. FEBS J. 2021 May;288(10):3186-3196. doi: 10.1111/febs.15619. Epub 2020 Nov 21. FEBS J. 2021. PMID: 33145969 Free PMC article.

10

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation.

Nizami S, Millar V, Arunasalam K, Zarganes-Tzitzikas T, Brough D, Tresadern G, Brennan PE, Davis JB, Ebner D, Di Daniel E. Nizami S, et al. Among authors: brough d. Sci Rep. 2021 Jul 28;11(1):15319. doi: 10.1038/s41598-021-94850-w. Sci Rep. 2021. PMID: 34321581 Free PMC article.

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