Brough D - Search Results

1

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.

Nizami S, Arunasalam K, Green J, Cook J, Lawrence CB, Zarganes-Tzitzikas T, Davis JB, Di Daniel E, Brough D. Nizami S, et al. Among authors: brough d. Immunology. 2021 Jan;162(1):84-91. doi: 10.1111/imm.13267. Epub 2020 Oct 30. Immunology. 2021. PMID: 32954500 Free PMC article.

2

Nuclear retention of IL-1 alpha by necrotic cells: a mechanism to dampen sterile inflammation.

Luheshi NM, McColl BW, Brough D. Luheshi NM, et al. Among authors: brough d. Eur J Immunol. 2009 Nov;39(11):2973-80. doi: 10.1002/eji.200939712. Eur J Immunol. 2009. PMID: 19839011 Free PMC article.

3

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages.

Luheshi NM, Giles JA, Lopez-Castejon G, Brough D. Luheshi NM, et al. Among authors: brough d. Eur J Immunol. 2012 Mar;42(3):716-25. doi: 10.1002/eji.201142079. Epub 2011 Dec 27. Eur J Immunol. 2012. PMID: 22105559 Free PMC article.

4

Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide.

Lawrence CB, Brough D, Knight EM. Lawrence CB, et al. Among authors: brough d. Dis Model Mech. 2012 Sep;5(5):649-59. doi: 10.1242/dmm.009068. Epub 2012 Feb 10. Dis Model Mech. 2012. PMID: 22328591 Free PMC article.

5

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury.

Savage CD, Lopez-Castejon G, Denes A, Brough D. Savage CD, et al. Among authors: brough d. Front Immunol. 2012 Sep 18;3:288. doi: 10.3389/fimmu.2012.00288. eCollection 2012. Front Immunol. 2012. PMID: 23024646 Free PMC article.

6

Zinc depletion regulates the processing and secretion of IL-1β.

Summersgill H, England H, Lopez-Castejon G, Lawrence CB, Luheshi NM, Pahle J, Mendes P, Brough D. Summersgill H, et al. Among authors: brough d. Cell Death Dis. 2014 Jan 30;5(1):e1040. doi: 10.1038/cddis.2013.547. Cell Death Dis. 2014. PMID: 24481454 Free PMC article.

7

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P. Baroja-Mazo A, et al. Among authors: brough d. Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952504

8

Apoptosis-associated speck-like protein containing a CARD forms specks but does not activate caspase-1 in the absence of NLRP3 during macrophage swelling.

Compan V, Martín-Sánchez F, Baroja-Mazo A, López-Castejón G, Gomez AI, Verkhratsky A, Brough D, Pelegrín P. Compan V, et al. Among authors: brough d. J Immunol. 2015 Feb 1;194(3):1261-73. doi: 10.4049/jimmunol.1301676. Epub 2014 Dec 31. J Immunol. 2015. PMID: 25552542 Free PMC article.

9

AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.

Denes A, Coutts G, Lénárt N, Cruickshank SM, Pelegrin P, Skinner J, Rothwell N, Allan SM, Brough D. Denes A, et al. Among authors: brough d. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4050-5. doi: 10.1073/pnas.1419090112. Epub 2015 Mar 16. Proc Natl Acad Sci U S A. 2015. PMID: 25775556 Free PMC article.

10

Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways.

Rivers-Auty J, Brough D. Rivers-Auty J, et al. Among authors: brough d. Eur J Immunol. 2015 Oct;45(10):2758-61. doi: 10.1002/eji.201545958. Epub 2015 Sep 21. Eur J Immunol. 2015. PMID: 26332156 Free article. Review.

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