Brotin E - Search Results

1

In vitro genotoxicity potential investigation of 7 oxy-PAHs.

Clergé A, Le Goff J, Brotin E, Abeillard E, Vaudorne I, Denoyelle C, Le Hegarat L, Delépée R. Clergé A, et al. Among authors: brotin e. Environ Mol Mutagen. 2023 Mar;64(3):176-186. doi: 10.1002/em.22531. Epub 2023 Feb 22. Environ Mol Mutagen. 2023. PMID: 36757094

2

Bcl-XL and MCL-1 constitute pertinent targets in ovarian carcinoma and their concomitant inhibition is sufficient to induce apoptosis.

Brotin E, Meryet-Figuière M, Simonin K, Duval RE, Villedieu M, Leroy-Dudal J, Saison-Behmoaras E, Gauduchon P, Denoyelle C, Poulain L. Brotin E, et al. Int J Cancer. 2010 Feb 15;126(4):885-95. doi: 10.1002/ijc.24787. Int J Cancer. 2010. PMID: 19634140 Free article.

3

Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells.

Simonin K, Brotin E, Dufort S, Dutoit S, Goux D, N'diaye M, Denoyelle C, Gauduchon P, Poulain L. Simonin K, et al. Among authors: brotin e. Mol Cancer Ther. 2009 Nov;8(11):3162-70. doi: 10.1158/1535-7163.MCT-09-0493. Epub 2009 Nov 3. Mol Cancer Ther. 2009. PMID: 19887550

4

Downregulation of Bcl-xL and Mcl-1 is sufficient to induce cell death in mesothelioma cells highly refractory to conventional chemotherapy.

Varin E, Denoyelle C, Brotin E, Meryet-Figuière M, Giffard F, Abeilard E, Goux D, Gauduchon P, Icard P, Poulain L. Varin E, et al. Among authors: brotin e. Carcinogenesis. 2010 Jun;31(6):984-93. doi: 10.1093/carcin/bgq026. Epub 2010 Feb 8. Carcinogenesis. 2010. PMID: 20142415

5

miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-XL and EGFR leading to BIM activation.

Denoyelle C, Lambert B, Meryet-Figuière M, Vigneron N, Brotin E, Lecerf C, Abeilard E, Giffard F, Louis MH, Gauduchon P, Juin P, Poulain L. Denoyelle C, et al. Among authors: brotin e. Cell Death Dis. 2014 Oct 9;5(10):e1445. doi: 10.1038/cddis.2014.389. Cell Death Dis. 2014. PMID: 25299770 Free PMC article.

6

An overview of long non-coding RNAs in ovarian cancers.

Meryet-Figuière M, Lambert B, Gauduchon P, Vigneron N, Brotin E, Poulain L, Denoyelle C. Meryet-Figuière M, et al. Among authors: brotin e. Oncotarget. 2016 Jul 12;7(28):44719-44734. doi: 10.18632/oncotarget.8089. Oncotarget. 2016. PMID: 26992233 Free PMC article. Review.

7

Atelocollagen-mediated in vivo siRNA transfection in ovarian carcinoma is influenced by tumor site, siRNA target and administration route.

Meryet-Figuière M, Lecerf C, Varin E, Coll JL, Louis MH, Dutoit S, Giffard F, Blanc-Fournier C, Hedir S, Vigneron N, Brotin E, Pelletier L, Josserand V, Denoyelle C, Poulain L. Meryet-Figuière M, et al. Among authors: brotin e. Oncol Rep. 2017 Oct;38(4):1949-1958. doi: 10.3892/or.2017.5882. Epub 2017 Aug 4. Oncol Rep. 2017. PMID: 28791387 Free PMC article.

8

Antitumor activity of nanoliposomes encapsulating the novobiocin analog 6BrCaQ in a triple-negative breast cancer model in mice.

Sauvage F, Fattal E, Al-Shaer W, Denis S, Brotin E, Denoyelle C, Blanc-Fournier C, Toussaint B, Messaoudi S, Alami M, Barratt G, Vergnaud-Gauduchon J. Sauvage F, et al. Among authors: brotin e. Cancer Lett. 2018 Sep 28;432:103-111. doi: 10.1016/j.canlet.2018.06.001. Epub 2018 Jun 5. Cancer Lett. 2018. PMID: 29883750

9

Structure-guided design of pyridoclax derivatives based on Noxa / Mcl-1 interaction mode.

Hedir S, De Giorgi M, Fogha J, De Pascale M, Weiswald LB, Brotin E, Marekha B, Denoyelle C, Denis C, Suzanne P, Gautier F, Juin P, Ligat L, Lopez F, Carlier L, Legay R, Bureau R, Rault S, Poulain L, Oliveira Santos JS, Voisin-Chiret AS. Hedir S, et al. Among authors: brotin e. Eur J Med Chem. 2018 Nov 5;159:357-380. doi: 10.1016/j.ejmech.2018.10.003. Epub 2018 Oct 4. Eur J Med Chem. 2018. PMID: 30308410

10

Functional miRNA Screening Identifies Wide-ranging Antitumor Properties of miR-3622b-5p and Reveals a New Therapeutic Combination Strategy in Ovarian Tumor Organoids.

Vernon M, Lambert B, Meryet-Figuière M, Brotin E, Weiswald LB, Paysant H, Vigneron N, Wambecke A, Abeilard E, Giffard F, Louis MH, Blanc-Fournier C, Gauduchon P, Poulain L, Denoyelle C. Vernon M, et al. Among authors: brotin e. Mol Cancer Ther. 2020 Jul;19(7):1506-1519. doi: 10.1158/1535-7163.MCT-19-0510. Epub 2020 May 5. Mol Cancer Ther. 2020. PMID: 32371581

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