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Page 1
Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer.
Steele NG, Biffi G, Kemp SB, Zhang Y, Drouillard D, Syu L, Hao Y, Oni TE, Brosnan E, Elyada E, Doshi A, Hansma C, Espinoza C, Abbas A, The S, Irizarry-Negron V, Halbrook CJ, Franks NE, Hoffman MT, Brown K, Carpenter ES, Nwosu ZC, Johnson C, Lima F, Anderson MA, Park Y, Crawford HC, Lyssiotis CA, Frankel TL, Rao A, Bednar F, Dlugosz AA, Preall JB, Tuveson DA, Allen BL, Pasca di Magliano M. Steele NG, et al. Among authors: brosnan e. Clin Cancer Res. 2021 Apr 1;27(7):2023-2037. doi: 10.1158/1078-0432.CCR-20-3715. Epub 2021 Jan 25. Clin Cancer Res. 2021. PMID: 33495315 Free PMC article.
Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell Death.
Froeling FEM, Swamynathan MM, Deschênes A, Chio IIC, Brosnan E, Yao MA, Alagesan P, Lucito M, Li J, Chang AY, Trotman LC, Belleau P, Park Y, Rogoff HA, Watson JD, Tuveson DA. Froeling FEM, et al. Among authors: brosnan e. Clin Cancer Res. 2019 Dec 1;25(23):7162-7174. doi: 10.1158/1078-0432.CCR-19-0302. Epub 2019 Sep 16. Clin Cancer Res. 2019. PMID: 31527169 Free PMC article.
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.
Oni TE, Biffi G, Baker LA, Hao Y, Tonelli C, Somerville TDD, Deschênes A, Belleau P, Hwang CI, Sánchez-Rivera FJ, Cox H, Brosnan E, Doshi A, Lumia RP, Khaledi K, Park Y, Trotman LC, Lowe SW, Krasnitz A, Vakoc CR, Tuveson DA. Oni TE, et al. Among authors: brosnan e. J Exp Med. 2020 Sep 7;217(9):e20192389. doi: 10.1084/jem.20192389. J Exp Med. 2020. PMID: 32633781 Free PMC article.
A mucus production programme promotes classical pancreatic ductal adenocarcinoma.
Tonelli C, Yordanov GN, Hao Y, Deschênes A, Hinds J, Belleau P, Klingbeil O, Brosnan E, Doshi A, Park Y, Hruban RH, Vakoc CR, Dobin A, Preall J, Tuveson DA. Tonelli C, et al. Among authors: brosnan e. Gut. 2024 May 10;73(6):941-954. doi: 10.1136/gutjnl-2023-329839. Gut. 2024. PMID: 38262672 Free PMC article.
Characterization of Shiga toxin-producing Escherichia coli presence, serogroups and risk factors from private groundwater sources in western Ireland.
Burke LP, Chique C, Fitzhenry K, Chueiri A, O'Connor L, Hooban B, Cahill N, Brosnan E, Olaore L, Sullivan E, Reilly L, Morris D, Hynds P, O'Dwyer J. Burke LP, et al. Among authors: brosnan e. Sci Total Environ. 2023 Mar 25;866:161302. doi: 10.1016/j.scitotenv.2022.161302. Epub 2022 Dec 30. Sci Total Environ. 2023. PMID: 36592918
Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial.
Yamazaki T, Gunderson AJ, Gilchrist M, Whiteford M, Kiely MX, Hayman A, O'Brien D, Ahmad R, Manchio JV, Fox N, McCarty K, Phillips M, Brosnan E, Vaccaro G, Li R, Simon M, Bernstein E, McCormick M, Yamasaki L, Wu Y, Drokin A, Carnahan T, To Y, Redmond WL, Lee B, Louie J, Hansen E, Solhjem MC, Cramer J, Urba WJ, Gough MJ, Crittenden MR, Young KH. Yamazaki T, et al. Among authors: brosnan e. Lancet Oncol. 2022 Sep;23(9):1189-1200. doi: 10.1016/S1470-2045(22)00446-6. Epub 2022 Aug 8. Lancet Oncol. 2022. PMID: 35952709 Clinical Trial.
Retrospective national cohort study of pregnancy outcomes for women with type 1 and type 2 diabetes mellitus in Republic of Ireland.
Newman C, Egan AM, Ahern T, Al-Kiyumi M, Bacon S, Bahaeldein E, Balan G, Brassill MJ, Breslin E, Brosnan E, Carmody L, Clarke H, Coogan Kelly C, Culliney L, Davern R, Durkan M, Elhilo K, Cullen E, Fenlon M, Ferry P, Gabir A, Guinan L, Hanlon G, Heffernan M, Higgins T, Hoashi S, Kgosidialwa O, Khamis A, Kinsley B, Kirwan B, James A, Kyithar P, Liew A, Malik I, Matthews L, McGurk C, McHugh C, Moloney Y, Murphy MS, Murphy P, Nagodra D, Noctor E, Nolan M, O'Connor A, O'Connor E, O'Halloran D, O'Mahoney L, O'Shea T, O'Sullivan EP, Peters M, Roberts G, Rooney H, Sharma J, Smyth A, Synnott M, Tarachand B, Tighe M, Todd M, Towers M, Tuthill A, Mahmood W, Yousif O, Dunne FP. Newman C, et al. Among authors: brosnan e. Diabetes Res Clin Pract. 2022 Jul;189:109947. doi: 10.1016/j.diabres.2022.109947. Epub 2022 Jun 13. Diabetes Res Clin Pract. 2022. PMID: 35709911 Free article.
Extreme hyponatraemia due to primary polydipsia and quetiapine-induced SIAD.
Mc Donald D, Mc Donnell T, Crowley RK, Brosnan E. Mc Donald D, et al. Among authors: brosnan e. Endocrinol Diabetes Metab Case Rep. 2021 Oct 1;2021:21-0028. doi: 10.1530/EDM-21-0028. Online ahead of print. Endocrinol Diabetes Metab Case Rep. 2021. PMID: 34653996 Free PMC article.
Diabetes care and pregnancy outcomes for women with pregestational diabetes in Ireland.
Newman C, Egan AM, Ahern T, Al-Kiyumi M, Balan G, Brassill MJ, Brosnan E, Carmody L, Clarke H, Coogan Kelly C, Culliney L, Davern R, Durkan M, Fenlon M, Ferry P, Hanlon G, Higgins T, Hoashi S, Khamis A, Kinsley B, Kirwan B, Kyithar P, Liew A, Matthews L, McGurk C, McHugh C, Murphy MS, Murphy P, Nagodra D, Noctor E, Nolan M, O'Connor E, O'Halloran D, O'Mahoney L, O'Sullivan E, Peters M, Roberts G, Rooney H, Smyth A, Tarachand B, Todd M, Tuthill A, Wan Mahmood WA, Yousif O, Dunne FP. Newman C, et al. Among authors: brosnan e. Diabetes Res Clin Pract. 2021 Mar;173:108685. doi: 10.1016/j.diabres.2021.108685. Epub 2021 Feb 3. Diabetes Res Clin Pract. 2021. PMID: 33548336
28 results