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Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12.
Cell Mol Immunol. 2023.
PMID: 37041314
Free PMC article.
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques.
Baardman J, Verberk SGS, van der Velden S, Gijbels MJJ, van Roomen CPPA, Sluimer JC, Broos JY, Griffith GR, Prange KHM, van Weeghel M, Lakbir S, Molenaar D, Meinster E, Neele AE, Kooij G, de Vries HE, Lutgens E, Wellen KE, de Winther MPJ, Van den Bossche J.
Baardman J, et al. Among authors: broos jy.
Nat Commun. 2020 Dec 8;11(1):6296. doi: 10.1038/s41467-020-20141-z.
Nat Commun. 2020.
PMID: 33293558
Free PMC article.
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Early-life stress and dietary fatty acids impact the brain lipid/oxylipin profile into adulthood, basally and in response to LPS.
Reemst K, Broos JY, Abbink MR, Cimetti C, Giera M, Kooij G, Korosi A.
Reemst K, et al. Among authors: broos jy.
Front Immunol. 2022 Sep 5;13:967437. doi: 10.3389/fimmu.2022.967437. eCollection 2022.
Front Immunol. 2022.
PMID: 36131915
Free PMC article.
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Association of Arachidonic Acid-Derived Lipid Mediators With Disease Severity in Patients With Relapsing and Progressive Multiple Sclerosis.
Broos JY, Loonstra FC, de Ruiter LRJ, Gouda M, Fung WH, Schoonheim MM, Heijink M, Strijbis EMM, Teunissen C, Killestein J, de Vries HE, Giera M, Uitdehaag BMJ, Kooij G.
Broos JY, et al.
Neurology. 2023 Aug 1;101(5):e533-e545. doi: 10.1212/WNL.0000000000207459. Epub 2023 Jun 8.
Neurology. 2023.
PMID: 37290971
Free PMC article.
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Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?
Broos JY, van der Burgt RTM, Konings J, Rijnsburger M, Werz O, de Vries HE, Giera M, Kooij G.
Broos JY, et al.
J Neuroinflammation. 2024 Jan 17;21(1):21. doi: 10.1186/s12974-023-02981-w.
J Neuroinflammation. 2024.
PMID: 38233951
Free PMC article.
Review.
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