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Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: broos jy. Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12. Cell Mol Immunol. 2023. PMID: 37041314 Free PMC article.
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques.
Baardman J, Verberk SGS, van der Velden S, Gijbels MJJ, van Roomen CPPA, Sluimer JC, Broos JY, Griffith GR, Prange KHM, van Weeghel M, Lakbir S, Molenaar D, Meinster E, Neele AE, Kooij G, de Vries HE, Lutgens E, Wellen KE, de Winther MPJ, Van den Bossche J. Baardman J, et al. Among authors: broos jy. Nat Commun. 2020 Dec 8;11(1):6296. doi: 10.1038/s41467-020-20141-z. Nat Commun. 2020. PMID: 33293558 Free PMC article.
Association of Arachidonic Acid-Derived Lipid Mediators With Disease Severity in Patients With Relapsing and Progressive Multiple Sclerosis.
Broos JY, Loonstra FC, de Ruiter LRJ, Gouda M, Fung WH, Schoonheim MM, Heijink M, Strijbis EMM, Teunissen C, Killestein J, de Vries HE, Giera M, Uitdehaag BMJ, Kooij G. Broos JY, et al. Neurology. 2023 Aug 1;101(5):e533-e545. doi: 10.1212/WNL.0000000000207459. Epub 2023 Jun 8. Neurology. 2023. PMID: 37290971 Free PMC article.