Brooks DG - Search Results

1

Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy.

Boukhaled GM, Gadalla R, Elsaesser HJ, Abd-Rabbo D, Quevedo R, Yang SYC, Guo M, Wang BX, Noamani B, Gray D, Lau SCM, Taylor K, Aung K, Spreafico A, Hansen AR, Saibil SD, Hirano N, Guidos C, Pugh TJ, McGaha TL, Ohashi PS, Sacher AG, Butler MO, Brooks DG. Boukhaled GM, et al. Among authors: brooks dg. Nat Immunol. 2022 Aug;23(8):1273-1283. doi: 10.1038/s41590-022-01262-7. Epub 2022 Jul 14. Nat Immunol. 2022. PMID: 35835962

2

IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection.

Brooks DG, Lee AM, Elsaesser H, McGavern DB, Oldstone MB. Brooks DG, et al. J Exp Med. 2008 Mar 17;205(3):533-41. doi: 10.1084/jem.20071948. Epub 2008 Mar 10. J Exp Med. 2008. PMID: 18332180 Free PMC article.

3

IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.

Brooks DG, Ha SJ, Elsaesser H, Sharpe AH, Freeman GJ, Oldstone MB. Brooks DG, et al. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20428-33. doi: 10.1073/pnas.0811139106. Epub 2008 Dec 15. Proc Natl Acad Sci U S A. 2008. PMID: 19075244 Free PMC article.

4

IL-21 is required to control chronic viral infection.

Elsaesser H, Sauer K, Brooks DG. Elsaesser H, et al. Among authors: brooks dg. Science. 2009 Jun 19;324(5934):1569-72. doi: 10.1126/science.1174182. Epub 2009 May 7. Science. 2009. PMID: 19423777 Free PMC article.

5

IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection.

Brooks DG, Walsh KB, Elsaesser H, Oldstone MB. Brooks DG, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3018-23. doi: 10.1073/pnas.0914500107. Epub 2010 Jan 26. Proc Natl Acad Sci U S A. 2010. PMID: 20133700 Free PMC article.

6

Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells.

Fahey LM, Wilson EB, Elsaesser H, Fistonich CD, McGavern DB, Brooks DG. Fahey LM, et al. Among authors: brooks dg. J Exp Med. 2011 May 9;208(5):987-99. doi: 10.1084/jem.20101773. Epub 2011 May 2. J Exp Med. 2011. PMID: 21536743 Free PMC article.

7

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.

Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. Kidani Y, et al. Among authors: brooks dg. Nat Immunol. 2013 May;14(5):489-99. doi: 10.1038/ni.2570. Epub 2013 Apr 7. Nat Immunol. 2013. PMID: 23563690 Free PMC article.

8

Blockade of chronic type I interferon signaling to control persistent LCMV infection.

Wilson EB, Yamada DH, Elsaesser H, Herskovitz J, Deng J, Cheng G, Aronow BJ, Karp CL, Brooks DG. Wilson EB, et al. Among authors: brooks dg. Science. 2013 Apr 12;340(6129):202-7. doi: 10.1126/science.1235208. Science. 2013. PMID: 23580528 Free PMC article.

9

Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection.

Osokine I, Snell LM, Cunningham CR, Yamada DH, Wilson EB, Elsaesser HJ, de la Torre JC, Brooks D. Osokine I, et al. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7409-14. doi: 10.1073/pnas.1401662111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799699 Free PMC article.

10

Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection.

Yamada DH, Elsaesser H, Lux A, Timmerman JM, Morrison SL, de la Torre JC, Nimmerjahn F, Brooks DG. Yamada DH, et al. Among authors: brooks dg. Immunity. 2015 Feb 17;42(2):379-390. doi: 10.1016/j.immuni.2015.01.005. Epub 2015 Feb 10. Immunity. 2015. PMID: 25680277 Free PMC article.

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