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Page 1
Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas CJ, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T. Romero R, et al. Among authors: bronson rt. Nat Med. 2017 Nov;23(11):1362-1368. doi: 10.1038/nm.4407. Epub 2017 Oct 2. Nat Med. 2017. PMID: 28967920 Free PMC article.
Rapid modelling of cooperating genetic events in cancer through somatic genome editing.
Sánchez-Rivera FJ, Papagiannakopoulos T, Romero R, Tammela T, Bauer MR, Bhutkar A, Joshi NS, Subbaraj L, Bronson RT, Xue W, Jacks T. Sánchez-Rivera FJ, et al. Among authors: bronson rt. Nature. 2014 Dec 18;516(7531):428-31. doi: 10.1038/nature13906. Epub 2014 Oct 22. Nature. 2014. PMID: 25337879 Free PMC article.
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.
Romero R, Sánchez-Rivera FJ, Westcott PMK, Mercer KL, Bhutkar A, Muir A, González Robles TJ, Lamboy Rodríguez S, Liao LZ, Ng SR, Li L, Colón CI, Naranjo S, Beytagh MC, Lewis CA, Hsu PP, Bronson RT, Vander Heiden MG, Jacks T. Romero R, et al. Among authors: bronson rt. Nat Cancer. 2020 Jun;1(6):589-602. doi: 10.1038/s43018-020-0071-1. Epub 2020 Jun 8. Nat Cancer. 2020. PMID: 34414377 Free PMC article.
Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma.
McFadden DG, Politi K, Bhutkar A, Chen FK, Song X, Pirun M, Santiago PM, Kim-Kiselak C, Platt JT, Lee E, Hodges E, Rosebrock AP, Bronson RT, Socci ND, Hannon GJ, Jacks T, Varmus H. McFadden DG, et al. Among authors: bronson rt. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6409-E6417. doi: 10.1073/pnas.1613601113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702896 Free PMC article.
Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung.
Concepcion CP, Ma S, LaFave LM, Bhutkar A, Liu M, DeAngelo LP, Kim JY, Del Priore I, Schoenfeld AJ, Miller M, Kartha VK, Westcott PMK, Sánchez-Rivera FJ, Meli K, Gupta M, Bronson RT, Riely GJ, Rekhtman N, Rudin CM, Kim CF, Regev A, Buenrostro JD, Jacks T. Concepcion CP, et al. Among authors: bronson rt. Cancer Discov. 2022 Feb;12(2):562-585. doi: 10.1158/2159-8290.CD-21-0248. Epub 2021 Sep 24. Cancer Discov. 2022. PMID: 34561242 Free PMC article.
Publisher Correction: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1.
Romero R, Sánchez-Rivera FJ, Westcott PMK, Mercer KL, Bhutkar A, Muir A, González Robles TJ, Rodríguez SL, Liao LZ, Ng SR, Li L, Colón CI, Naranjo S, Beytagh MC, Lewis CA, Hsu PP, Bronson RT, Vander Heiden MG, Jacks T. Romero R, et al. Among authors: bronson rt. Nat Cancer. 2020 Sep;1(9):935. doi: 10.1038/s43018-020-00118-z. Nat Cancer. 2020. PMID: 35121957 No abstract available.
CRISPR-mediated direct mutation of cancer genes in the mouse liver.
Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. Xue W, et al. Nature. 2014 Oct 16;514(7522):380-4. doi: 10.1038/nature13589. Epub 2014 Aug 6. Nature. 2014. PMID: 25119044 Free PMC article.
544 results