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The importance of antimicrobial resistance in medical mycology.
Gow NAR, Johnson C, Berman J, Coste AT, Cuomo CA, Perlin DS, Bicanic T, Harrison TS, Wiederhold N, Bromley M, Chiller T, Edgar K. Gow NAR, et al. Among authors: bromley m. Nat Commun. 2022 Sep 12;13(1):5352. doi: 10.1038/s41467-022-32249-5. Nat Commun. 2022. PMID: 36097014 Free PMC article. Review.
F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase.
Oliver JD, Sibley GEM, Beckmann N, Dobb KS, Slater MJ, McEntee L, du Pré S, Livermore J, Bromley MJ, Wiederhold NP, Hope WW, Kennedy AJ, Law D, Birch M. Oliver JD, et al. Among authors: bromley mj. Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12809-12814. doi: 10.1073/pnas.1608304113. Epub 2016 Oct 25. Proc Natl Acad Sci U S A. 2016. PMID: 27791100 Free PMC article.
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus.
Furukawa T, van Rhijn N, Fraczek M, Gsaller F, Davies E, Carr P, Gago S, Fortune-Grant R, Rahman S, Gilsenan JM, Houlder E, Kowalski CH, Raj S, Paul S, Cook P, Parker JE, Kelly S, Cramer RA, Latgé JP, Moye-Rowley S, Bignell E, Bowyer P, Bromley MJ. Furukawa T, et al. Among authors: bromley mj. Nat Commun. 2020 Jan 22;11(1):427. doi: 10.1038/s41467-019-14191-1. Nat Commun. 2020. PMID: 31969561 Free PMC article.
Tackling the emerging threat of antifungal resistance to human health.
Fisher MC, Alastruey-Izquierdo A, Berman J, Bicanic T, Bignell EM, Bowyer P, Bromley M, Brüggemann R, Garber G, Cornely OA, Gurr SJ, Harrison TS, Kuijper E, Rhodes J, Sheppard DC, Warris A, White PL, Xu J, Zwaan B, Verweij PE. Fisher MC, et al. Among authors: bromley m. Nat Rev Microbiol. 2022 Sep;20(9):557-571. doi: 10.1038/s41579-022-00720-1. Epub 2022 Mar 29. Nat Rev Microbiol. 2022. PMID: 35352028 Free PMC article. Review.
Fungal oxylipins direct programmed developmental switches in filamentous fungi.
Niu M, Steffan BN, Fischer GJ, Venkatesh N, Raffa NL, Wettstein MA, Bok JW, Greco C, Zhao C, Berthier E, Oliw E, Beebe D, Bromley M, Keller NP. Niu M, et al. Among authors: bromley m. Nat Commun. 2020 Oct 14;11(1):5158. doi: 10.1038/s41467-020-18999-0. Nat Commun. 2020. PMID: 33056992 Free PMC article.
162 results