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The centrosome protein AKNA regulates neurogenesis via microtubule organization.
Camargo Ortega G, Falk S, Johansson PA, Peyre E, Broix L, Sahu SK, Hirst W, Schlichthaerle T, De Juan Romero C, Draganova K, Vinopal S, Chinnappa K, Gavranovic A, Karakaya T, Steininger T, Merl-Pham J, Feederle R, Shao W, Shi SH, Hauck SM, Jungmann R, Bradke F, Borrell V, Geerlof A, Reber S, Tiwari VK, Huttner WB, Wilsch-Bräuninger M, Nguyen L, Götz M. Camargo Ortega G, et al. Among authors: broix l. Nature. 2019 Mar;567(7746):113-117. doi: 10.1038/s41586-019-0962-4. Epub 2019 Feb 20. Nature. 2019. PMID: 30787442 Free article.
Cerebral cortex development: an outside-in perspective.
Agirman G, Broix L, Nguyen L. Agirman G, et al. Among authors: broix l. FEBS Lett. 2017 Dec;591(24):3978-3992. doi: 10.1002/1873-3468.12924. Epub 2017 Dec 14. FEBS Lett. 2017. PMID: 29194577 Free article. Review.
Publisher Correction: ATP-citrate lyase promotes axonal transport across species.
Even A, Morelli G, Turchetto S, Shilian M, Bail RL, Laguesse S, Krusy N, Brisker A, Brandis A, Inbar S, Chariot A, Saudou F, Dietrich P, Dragatsis I, Brone B, Broix L, Rigo JM, Weil M, Nguyen L. Even A, et al. Among authors: broix l. Nat Commun. 2021 Nov 12;12(1):6678. doi: 10.1038/s41467-021-26998-y. Nat Commun. 2021. PMID: 34772940 Free PMC article. No abstract available.
ATP-citrate lyase promotes axonal transport across species.
Even A, Morelli G, Turchetto S, Shilian M, Bail RL, Laguesse S, Krusy N, Brisker A, Brandis A, Inbar S, Chariot A, Saudou F, Dietrich P, Dragatsis I, Brone B, Broix L, Rigo JM, Weil M, Nguyen L. Even A, et al. Among authors: broix l. Nat Commun. 2021 Oct 7;12(1):5878. doi: 10.1038/s41467-021-25786-y. Nat Commun. 2021. PMID: 34620845 Free PMC article.
TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis.
Ivanova EL, Gilet JG, Sulimenko V, Duchon A, Rudolf G, Runge K, Collins SC, Asselin L, Broix L, Drouot N, Tilly P, Nusbaum P, Vincent A, Magnant W, Skory V, Birling MC, Pavlovic G, Godin JD, Yalcin B, Hérault Y, Dráber P, Chelly J, Hinckelmann MV. Ivanova EL, et al. Among authors: broix l. Nat Commun. 2019 May 13;10(1):2129. doi: 10.1038/s41467-019-10081-8. Nat Commun. 2019. PMID: 31086189 Free PMC article.
ATAT1-enriched vesicles promote microtubule acetylation via axonal transport.
Even A, Morelli G, Broix L, Scaramuzzino C, Turchetto S, Gladwyn-Ng I, Le Bail R, Shilian M, Freeman S, Magiera MM, Jijumon AS, Krusy N, Malgrange B, Brone B, Dietrich P, Dragatsis I, Janke C, Saudou F, Weil M, Nguyen L. Even A, et al. Among authors: broix l. Sci Adv. 2019 Dec 18;5(12):eaax2705. doi: 10.1126/sciadv.aax2705. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31897425 Free PMC article.
Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton-Smith J, Pagnamenta AT, Metcalfe KA, Isidor B, Louvier UW, Poduri A, Taylor JC, Tilly P, Poirier K, Saillour Y, Lebrun N, Stemmelen T, Rudolf G, Muraca G, Saintpierre B, Elmorjani A; Deciphering Developmental Disorders study; Moïse M, Weirauch NB, Guerrini R, Boland A, Olaso R, Masson C, Tripathy R, Keays D, Beldjord C, Nguyen L, Godin J, Kini U, Nischké P, Deleuze JF, Bahi-Buisson N, Sumara I, Hinckelmann MV, Chelly J. Broix L, et al. Nat Genet. 2016 Nov;48(11):1349-1358. doi: 10.1038/ng.3676. Epub 2016 Oct 3. Nat Genet. 2016. PMID: 27694961 Free PMC article.
16 results