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The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape.
de Jong MME, Kellermayer Z, Papazian N, Tahri S, Hofste Op Bruinink D, Hoogenboezem R, Sanders MA, van de Woestijne PC, Bos PK, Khandanpour C, Vermeulen J, Moreau P, van Duin M, Broijl A, Sonneveld P, Cupedo T. de Jong MME, et al. Among authors: broijl a. Nat Immunol. 2021 Jun;22(6):769-780. doi: 10.1038/s41590-021-00931-3. Epub 2021 May 20. Nat Immunol. 2021. PMID: 34017122 Clinical Trial.
Prediction of high- and low-risk multiple myeloma based on gene expression and the International Staging System.
Kuiper R, van Duin M, van Vliet MH, Broijl A, van der Holt B, El Jarari L, van Beers EH, Mulligan G, Avet-Loiseau H, Gregory WM, Morgan G, Goldschmidt H, Lokhorst HM, Sonneveld P. Kuiper R, et al. Among authors: broijl a. Blood. 2015 Oct 22;126(17):1996-2004. doi: 10.1182/blood-2015-05-644039. Epub 2015 Sep 1. Blood. 2015. PMID: 26330243 Free PMC article.
European Myeloma Network guidelines for the management of multiple myeloma-related complications.
Terpos E, Kleber M, Engelhardt M, Zweegman S, Gay F, Kastritis E, van de Donk NW, Bruno B, Sezer O, Broijl A, Bringhen S, Beksac M, Larocca A, Hajek R, Musto P, Johnsen HE, Morabito F, Ludwig H, Cavo M, Einsele H, Sonneveld P, Dimopoulos MA, Palumbo A; European Myeloma Network. Terpos E, et al. Among authors: broijl a. Haematologica. 2015 Oct;100(10):1254-66. doi: 10.3324/haematol.2014.117176. Haematologica. 2015. PMID: 26432383 Free PMC article.
Phase I/II trial of weekly bortezomib with lenalidomide and dexamethasone in first relapse or primary refractory myeloma.
Broijl A, Kersten MJ, Alemayehu WG, Levin MD, de Weerdt O, Vellenga E, Meijer E, Wittebol S, Tanis BC, Cornelisse PB, Stevens-Kroef M, Bos GM, Wijermans PW, Lokhorst H, Sonneveld P. Broijl A, et al. Haematologica. 2016 Apr;101(4):e149-52. doi: 10.3324/haematol.2015.132431. Epub 2015 Dec 11. Haematologica. 2016. PMID: 26659914 Free PMC article. Clinical Trial. No abstract available.
Treatment of relapsed and refractory multiple myeloma.
Sonneveld P, Broijl A. Sonneveld P, et al. Among authors: broijl a. Haematologica. 2016 Apr;101(4):396-406. doi: 10.3324/haematol.2015.129189. Haematologica. 2016. PMID: 27033237 Free PMC article. Review.
Treatment of relapsed and refractory multiple myeloma.
Sonneveld P, Broijl A. Sonneveld P, et al. Among authors: broijl a. Haematologica. 2016 Aug;101(8):995. doi: 10.3324/haematol.2016.148882. Haematologica. 2016. PMID: 27478200 Free PMC article. No abstract available.
Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma.
Nijhof IS, Franssen LE, Levin MD, Bos GMJ, Broijl A, Klein SK, Koene HR, Bloem AC, Beeker A, Faber LM, van der Spek E, Ypma PF, Raymakers R, van Spronsen DJ, Westerweel PE, Oostvogels R, van Velzen J, van Kessel B, Mutis T, Sonneveld P, Zweegman S, Lokhorst HM, van de Donk NWCJ. Nijhof IS, et al. Among authors: broijl a. Blood. 2016 Nov 10;128(19):2297-2306. doi: 10.1182/blood-2016-07-729236. Epub 2016 Sep 19. Blood. 2016. PMID: 27647864 Free article. Clinical Trial.
Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients.
Franssen LE, Nijhof IS, Couto S, Levin MD, Bos GMJ, Broijl A, Klein SK, Ren Y, Wang M, Koene HR, Bloem AC, Beeker A, Faber LM, van der Spek E, Raymakers R, Leguit RJ, Sonneveld P, Zweegman S, Lokhorst H, Mutis T, Thakurta A, Qian X, van de Donk NWCJ. Franssen LE, et al. Among authors: broijl a. Haematologica. 2018 Aug;103(8):e368-e371. doi: 10.3324/haematol.2017.186601. Epub 2018 Mar 15. Haematologica. 2018. PMID: 29545338 Free PMC article. No abstract available.
49 results