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Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding.
Adriaenssens A, Broichhagen J, de Bray A, Ast J, Hasib A, Jones B, Tomas A, Burgos NF, Woodward O, Lewis J, O'Flaherty E, El K, Cui C, Harada N, Inagaki N, Campbell J, Brierley D, Hodson DJ, Samms R, Gribble F, Reimann F. Adriaenssens A, et al. Among authors: broichhagen j. JCI Insight. 2023 May 22;8(10):e164921. doi: 10.1172/jci.insight.164921. JCI Insight. 2023. PMID: 37212283 Free PMC article.
Optical Control of Insulin Secretion Using an Incretin Switch.
Broichhagen J, Podewin T, Meyer-Berg H, von Ohlen Y, Johnston NR, Jones BJ, Bloom SR, Rutter GA, Hoffmann-Röder A, Hodson DJ, Trauner D. Broichhagen J, et al. Angew Chem Int Ed Engl. 2015 Dec 14;54(51):15565-9. doi: 10.1002/anie.201506384. Epub 2015 Nov 2. Angew Chem Int Ed Engl. 2015. PMID: 26585495 Free PMC article.
Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.
Broichhagen J, Johnston NR, von Ohlen Y, Meyer-Berg H, Jones BJ, Bloom SR, Rutter GA, Trauner D, Hodson DJ. Broichhagen J, et al. Angew Chem Int Ed Engl. 2016 May 4;55(19):5865-8. doi: 10.1002/anie.201600957. Epub 2016 Apr 5. Angew Chem Int Ed Engl. 2016. PMID: 27059784 Free PMC article.
Remote control of glucose homeostasis in vivo using photopharmacology.
Mehta ZB, Johnston NR, Nguyen-Tu MS, Broichhagen J, Schultz P, Larner DP, Leclerc I, Trauner D, Rutter GA, Hodson DJ. Mehta ZB, et al. Among authors: broichhagen j. Sci Rep. 2017 Mar 22;7(1):291. doi: 10.1038/s41598-017-00397-0. Sci Rep. 2017. PMID: 28331198 Free PMC article.
Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.
Podewin T, Ast J, Broichhagen J, Fine NHF, Nasteska D, Leippe P, Gailer M, Buenaventura T, Kanda N, Jones BJ, M'Kadmi C, Baneres JL, Marie J, Tomas A, Trauner D, Hoffmann-Röder A, Hodson DJ. Podewin T, et al. Among authors: broichhagen j. ACS Cent Sci. 2018 Feb 28;4(2):166-179. doi: 10.1021/acscentsci.7b00237. Epub 2018 Jan 16. ACS Cent Sci. 2018. PMID: 29532016 Free PMC article.
Optical control of GPR40 signalling in pancreatic β-cells.
Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. Frank JA, et al. Among authors: broichhagen j. Chem Sci. 2017 Nov 1;8(11):7604-7610. doi: 10.1039/c7sc01475a. Epub 2017 Aug 30. Chem Sci. 2017. PMID: 29568424 Free PMC article.
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.
Ast J, Arvaniti A, Fine NHF, Nasteska D, Ashford FB, Stamataki Z, Koszegi Z, Bacon A, Jones BJ, Lucey MA, Sasaki S, Brierley DI, Hastoy B, Tomas A, D'Agostino G, Reimann F, Lynn FC, Reissaus CA, Linnemann AK, D'Este E, Calebiro D, Trapp S, Johnsson K, Podewin T, Broichhagen J, Hodson DJ. Ast J, et al. Among authors: broichhagen j. Nat Commun. 2020 Jan 24;11(1):467. doi: 10.1038/s41467-020-14309-w. Nat Commun. 2020. PMID: 31980626 Free PMC article.
76 results