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Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy.
Campiani G, Khan T, Ulivieri C, Staiano L, Papulino C, Magnano S, Nathwani S, Ramunno A, Lucena-Agell D, Relitti N, Federico S, Pozzetti L, Carullo G, Casagni A, Brogi S, Vanni F, Galatello P, Ghanim M, McCabe N, Lamponi S, Valoti M, Ibrahim O, O'Sullivan J, Turkington R, Kelly VP, VanWemmel R, Díaz JF, Gemma S, Zisterer D, Altucci L, De Matteis A, Butini S, Benedetti R. Campiani G, et al. Among authors: brogi s. Eur J Med Chem. 2022 May 5;235:114274. doi: 10.1016/j.ejmech.2022.114274. Epub 2022 Mar 20. Eur J Med Chem. 2022. PMID: 35344902
New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways.
Martelli A, Omrani M, Zarghooni M, Citi V, Brogi S, Calderone V, Sureda A, Lorzadeh S, da Silva Rosa SC, Grabarek BO, Staszkiewicz R, Los MJ, Nabavi SF, Nabavi SM, Mehrbod P, Klionsky DJ, Ghavami S. Martelli A, et al. Among authors: brogi s. Cancers (Basel). 2022 Nov 26;14(23):5839. doi: 10.3390/cancers14235839. Cancers (Basel). 2022. PMID: 36497321 Free PMC article. Review.
Exploring Citrus sinensis Phytochemicals as Potential Inhibitors for Breast Cancer Genes BRCA1 and BRCA2 Using Pharmacophore Modeling, Molecular Docking, MD Simulations, and DFT Analysis.
Zia M, Parveen S, Shafiq N, Rashid M, Farooq A, Dauelbait M, Shahab M, Salamatullah AM, Brogi S, Bourhia M. Zia M, et al. Among authors: brogi s. ACS Omega. 2024 Jan 3;9(2):2161-2182. doi: 10.1021/acsomega.3c05098. eCollection 2024 Jan 16. ACS Omega. 2024. PMID: 38250382 Free PMC article.
Resveratrol-like Compounds as SIRT1 Activators.
Ciccone L, Piragine E, Brogi S, Camodeca C, Fucci R, Calderone V, Nencetti S, Martelli A, Orlandini E. Ciccone L, et al. Among authors: brogi s. Int J Mol Sci. 2022 Dec 1;23(23):15105. doi: 10.3390/ijms232315105. Int J Mol Sci. 2022. PMID: 36499460 Free PMC article.
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: further structure-activity relationships, in vivo studies, and preliminary toxicity profiling.
Gemma S, Camodeca C, Sanna Coccone S, Joshi BP, Bernetti M, Moretti V, Brogi S, Bonache de Marcos MC, Savini L, Taramelli D, Basilico N, Parapini S, Rottmann M, Brun R, Lamponi S, Caccia S, Guiso G, Summers RL, Martin RE, Saponara S, Gorelli B, Novellino E, Campiani G, Butini S. Gemma S, et al. Among authors: brogi s. J Med Chem. 2012 Aug 9;55(15):6948-67. doi: 10.1021/jm300802s. Epub 2012 Jul 27. J Med Chem. 2012. PMID: 22783984
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1.
Gemma S, Giovani S, Brindisi M, Tripaldi P, Brogi S, Savini L, Fiorini I, Novellino E, Butini S, Campiani G, Penzo M, Blackman MJ. Gemma S, et al. Among authors: brogi s. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5317-21. doi: 10.1016/j.bmcl.2012.06.023. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22796182
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents.
Gemma S, Camodeca C, Brindisi M, Brogi S, Kukreja G, Kunjir S, Gabellieri E, Lucantoni L, Habluetzel A, Taramelli D, Basilico N, Gualdani R, Tadini-Buoninsegni F, Bartolommei G, Moncelli MR, Martin RE, Summers RL, Lamponi S, Savini L, Fiorini I, Valoti M, Novellino E, Campiani G, Butini S. Gemma S, et al. Among authors: brogi s. J Med Chem. 2012 Dec 13;55(23):10387-404. doi: 10.1021/jm300831b. Epub 2012 Nov 21. J Med Chem. 2012. PMID: 23145816
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Cappelli A, Manini M, Valenti S, Castriconi F, Giuliani G, Anzini M, Brogi S, Butini S, Gemma S, Campiani G, Giorgi G, Mennuni L, Lanza M, Giordani A, Caselli G, Letari O, Makovec F. Cappelli A, et al. Among authors: brogi s. Eur J Med Chem. 2013 May;63:85-94. doi: 10.1016/j.ejmech.2013.01.044. Epub 2013 Feb 8. Eur J Med Chem. 2013. PMID: 23466604
132 results