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CRISPR-Cas knockout of miR21 reduces glioma growth.
Nieland L, van Solinge TS, Cheah PS, Morsett LM, El Khoury J, Rissman JI, Kleinstiver BP, Broekman MLD, Breakefield XO, Abels ER. Nieland L, et al. Among authors: broekman mld. Mol Ther Oncolytics. 2022 Apr 6;25:121-136. doi: 10.1016/j.omto.2022.04.001. eCollection 2022 Jun 16. Mol Ther Oncolytics. 2022. PMID: 35572197 Free PMC article.
Preventing growth of brain tumors by creating a zone of resistance.
Maguire CA, Meijer DH, LeRoy SG, Tierney LA, Broekman ML, Costa FF, Breakefield XO, Stemmer-Rachamimov A, Sena-Esteves M. Maguire CA, et al. Mol Ther. 2008 Oct;16(10):1695-702. doi: 10.1038/mt.2008.168. Epub 2008 Aug 19. Mol Ther. 2008. PMID: 18714312 Free PMC article.
Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells.
de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. de Vrij J, et al. Int J Cancer. 2015 Oct 1;137(7):1630-42. doi: 10.1002/ijc.29521. Epub 2015 Apr 7. Int J Cancer. 2015. PMID: 25802036 Free article.
Glioma EVs Contribute to Immune Privilege in the Brain.
Abels ER, Broekman MLD, Breakefield XO, Maas SLN. Abels ER, et al. Among authors: broekman mld. Trends Cancer. 2019 Jul;5(7):393-396. doi: 10.1016/j.trecan.2019.05.006. Epub 2019 Jun 4. Trends Cancer. 2019. PMID: 31311653 Free PMC article. Review.
Nanocarrier-based drug combination therapy for glioblastoma.
Zhao M, van Straten D, Broekman MLD, Préat V, Schiffelers RM. Zhao M, et al. Among authors: broekman mld. Theranostics. 2020 Jan 1;10(3):1355-1372. doi: 10.7150/thno.38147. eCollection 2020. Theranostics. 2020. PMID: 31938069 Free PMC article. Review.
179 results