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Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities.
Oikemus SR, Pfister EL, Sapp E, Chase KO, Kennington LA, Hudgens E, Miller R, Zhu LJ, Chaudhary A, Mick EO, Sena-Esteves M, Wolfe SA, DiFiglia M, Aronin N, Brodsky MH. Oikemus SR, et al. Among authors: brodsky mh. Hum Gene Ther. 2022 Jan;33(1-2):25-36. doi: 10.1089/hum.2020.323. Hum Gene Ther. 2022. PMID: 34376056 Free PMC article.
Editing out five Serpina1 paralogs to create a mouse model of genetic emphysema.
Borel F, Sun H, Zieger M, Cox A, Cardozo B, Li W, Oliveira G, Davis A, Gruntman A, Flotte TR, Brodsky MH, Hoffman AM, Elmallah MK, Mueller C. Borel F, et al. Among authors: brodsky mh. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2788-2793. doi: 10.1073/pnas.1713689115. Epub 2018 Feb 16. Proc Natl Acad Sci U S A. 2018. PMID: 29453277 Free PMC article.
p53 represses class switch recombination to IgG2a through its antioxidant function.
Guikema JE, Schrader CE, Brodsky MH, Linehan EK, Richards A, El Falaky N, Li DH, Sluss HK, Szomolanyi-Tsuda E, Stavnezer J. Guikema JE, et al. Among authors: brodsky mh. J Immunol. 2010 Jun 1;184(11):6177-87. doi: 10.4049/jimmunol.0904085. Epub 2010 May 5. J Immunol. 2010. PMID: 20483782 Free PMC article.
79 results