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The Synthetic Peptide LyeTx I mn∆K, Derived from Lycosa erythrognatha Spider Toxin, Is Active against Methicillin-Resistant Staphylococcus aureus (MRSA) In Vitro and In Vivo.
Vieira APGC, de Souza AN, Lima WG, Brito JCM, Simião DC, Gonçalves LVR, Cordeiro LPB, de Oliveira Scoaris D, Fernandes SOA, Resende JM, Bechinger B, Verly RM, de Lima ME. Vieira APGC, et al. Among authors: brito jcm. Antibiotics (Basel). 2024 Mar 8;13(3):248. doi: 10.3390/antibiotics13030248. Antibiotics (Basel). 2024. PMID: 38534683 Free PMC article.
A short synthetic peptide, based on LyeTx I from Lycosa erythrognatha venom, shows potential to treat pneumonia caused by carbapenem-resistant Acinetobacter baumannii without detectable resistance.
Lima WG, Brito JCM, de Lima ME, Pizarro ACST, Vianna MAMM, de Paiva MC, de Assis DCS, Cardoso VN, Fernandes SOA. Lima WG, et al. Among authors: brito jcm. J Antibiot (Tokyo). 2021 Jul;74(7):425-434. doi: 10.1038/s41429-021-00421-6. Epub 2021 May 10. J Antibiot (Tokyo). 2021. PMID: 33972716
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