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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain.
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D, Brunmeir R, Yeap YJ, O'Brien NL, Groet J, Shao X, Havlicek S, Dunn NR, Kvartsberg H, Brinkmalm G, Hithersay R, Startin C, Hamburg S, Phillips M, Pervushin K, Turmaine M, Wallon D, Rovelet-Lecrux A, Soininen H, Volpi E, Martin JE, Foo JN, Becker DL, Rostagno A, Ghiso J, Krsnik Ž, Šimić G, Kostović I, Mitrečić D; LonDownS Consortium; Francis PT, Blennow K, Strydom A, Hardy J, Zetterberg H, Nižetić D. Alić I, et al. Among authors: brinkmalm g. Mol Psychiatry. 2021 Oct;26(10):5766-5788. doi: 10.1038/s41380-020-0806-5. Epub 2020 Jul 10. Mol Psychiatry. 2021. PMID: 32647257 Free PMC article.
Clinical proteomics in neurodegenerative disorders.
Zetterberg H, Rüetschi U, Portelius E, Brinkmalm G, Andreasson U, Blennow K, Brinkmalm A. Zetterberg H, et al. Among authors: brinkmalm a, brinkmalm g. Acta Neurol Scand. 2008 Jul;118(1):1-11. doi: 10.1111/j.1600-0404.2007.00985.x. Epub 2008 Feb 13. Acta Neurol Scand. 2008. PMID: 18279484 Review.
Characterization of tau in cerebrospinal fluid using mass spectrometry.
Portelius E, Hansson SF, Tran AJ, Zetterberg H, Grognet P, Vanmechelen E, Höglund K, Brinkmalm G, Westman-Brinkmalm A, Nordhoff E, Blennow K, Gobom J. Portelius E, et al. Among authors: brinkmalm g. J Proteome Res. 2008 May;7(5):2114-20. doi: 10.1021/pr7008669. Epub 2008 Mar 20. J Proteome Res. 2008. PMID: 18351740
Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative diseases.
Westman-Brinkmalm A, Ruetschi U, Portelius E, Andreasson U, Brinkmalm G, Karlsson G, Hansson S, Zetterberg H, Blennow K. Westman-Brinkmalm A, et al. Among authors: brinkmalm g. Front Biosci (Landmark Ed). 2009 Jan 1;14(5):1793-806. doi: 10.2741/3341. Front Biosci (Landmark Ed). 2009. PMID: 19273163 Free article. Review.
A novel pathway for amyloid precursor protein processing.
Portelius E, Price E, Brinkmalm G, Stiteler M, Olsson M, Persson R, Westman-Brinkmalm A, Zetterberg H, Simon AJ, Blennow K. Portelius E, et al. Among authors: brinkmalm g. Neurobiol Aging. 2011 Jun;32(6):1090-8. doi: 10.1016/j.neurobiolaging.2009.06.002. Epub 2009 Jul 14. Neurobiol Aging. 2011. PMID: 19604603
113 results