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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation.
Masle-Farquhar E, Jackson KJL, Peters TJ, Al-Eryani G, Singh M, Payne KJ, Rao G, Avery DT, Apps G, Kingham J, Jara CJ, Skvortsova K, Swarbrick A, Ma CS, Suan D, Uzel G, Chua I, Leiding JW, Heiskanen K, Preece K, Kainulainen L, O'Sullivan M, Cooper MA, Seppänen MRJ, Mustjoki S, Brothers S, Vogel TP, Brink R, Tangye SG, Reed JH, Goodnow CC. Masle-Farquhar E, et al. Among authors: brink r. Immunity. 2022 Dec 13;55(12):2386-2404.e8. doi: 10.1016/j.immuni.2022.11.001. Epub 2022 Nov 28. Immunity. 2022. PMID: 36446385 Free article.
β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling.
Thai LM, O'Reilly L, Reibe-Pal S, Sue N, Holliday H, Small L, Schmitz-Peiffer C, Dhenni R, Wang-Wei Tsai V, Norris N, Yau B, Zhang X, Lee K, Yan C, Shi YC, Kebede MA, Brink R, Cooney GJ, Irvine KM, Breit SN, Phan TG, Swarbrick A, Biden TJ. Thai LM, et al. Among authors: brink r. iScience. 2023 Mar 22;26(4):106477. doi: 10.1016/j.isci.2023.106477. eCollection 2023 Apr 21. iScience. 2023. PMID: 37091234 Free PMC article.
Apoptotic cell fragments locally activate tingible body macrophages in the germinal center.
Grootveld AK, Kyaw W, Panova V, Lau AWY, Ashwin E, Seuzaret G, Dhenni R, Bhattacharyya ND, Khoo WH, Biro M, Mitra T, Meyer-Hermann M, Bertolino P, Tanaka M, Hume DA, Croucher PI, Brink R, Nguyen A, Bannard O, Phan TG. Grootveld AK, et al. Among authors: brink r. Cell. 2023 Mar 16;186(6):1144-1161.e18. doi: 10.1016/j.cell.2023.02.004. Epub 2023 Mar 2. Cell. 2023. PMID: 36868219 Free PMC article.
Inhibition of MERTK reduces organ fibrosis in mouse models of fibrotic disease.
Pan Z, El Sharkway R, Bayoumi A, Metwally M, Gloss BS, Brink R, Lu DB, Liddle C, Alqahtani SA, Yu J, O'Connell PJ, George J, Eslam M. Pan Z, et al. Among authors: brink r. Sci Transl Med. 2024 Apr 3;16(741):eadj0133. doi: 10.1126/scitranslmed.adj0133. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569018
Group schema therapy combined with psychomotor therapy for older adults with a personality disorder: an open-label, multicentre, randomised controlled trial.
Veenstra-Spruit MS, Bouman R, van Dijk SD, van Asselt AD, van Alphen SP, Veenstra DH, de Ruiter M, Troost SE, Lammers MW, Vulker F, Smeets-Janssen MM, van den Brink RH, Voshaar RCO. Veenstra-Spruit MS, et al. Among authors: van den brink rh. Lancet Healthy Longev. 2024 Apr;5(4):e245-e254. doi: 10.1016/S2666-7568(24)00001-1. Lancet Healthy Longev. 2024. PMID: 38555919 Free article.
443 results