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A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
J Exp Med. 2021 Apr 5;218(4):e20201637. doi: 10.1084/jem.20201637.
J Exp Med. 2021.
PMID: 33620419
Free PMC article.
Clinical Trial.
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel.
Liu C, Reese R, Vu S, Rougé L, Shields SD, Kakiuchi-Kiyota S, Chen H, Johnson K, Shi YP, Chernov-Rogan T, Greiner DMZ, Kohli PB, Hackos D, Brillantes B, Tam C, Li T, Wang J, Safina B, Magnuson S, Volgraf M, Payandeh J, Zheng J, Rohou A, Chen J.
Liu C, et al. Among authors: brillantes b.
Neuron. 2021 Jan 20;109(2):273-284.e4. doi: 10.1016/j.neuron.2020.10.014. Epub 2020 Nov 4.
Neuron. 2021.
PMID: 33152265
Free PMC article.
Item in Clipboard
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist.
Ahuja S, Mukund S, Deng L, Khakh K, Chang E, Ho H, Shriver S, Young C, Lin S, Johnson JP Jr, Wu P, Li J, Coons M, Tam C, Brillantes B, Sampang H, Mortara K, Bowman KK, Clark KR, Estevez A, Xie Z, Verschoof H, Grimwood M, Dehnhardt C, Andrez JC, Focken T, Sutherlin DP, Safina BS, Starovasnik MA, Ortwine DF, Franke Y, Cohen CJ, Hackos DH, Koth CM, Payandeh J.
Ahuja S, et al. Among authors: brillantes b.
Science. 2015 Dec 18;350(6267):aac5464. doi: 10.1126/science.aac5464.
Science. 2015.
PMID: 26680203
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Semiautomated Small-Scale Purification Method for High-Throughput Expression Analysis of Recombinant Proteins.
Kraft E, Franke Y, Heeringa K, Shriver S, Zilberleyb I, Kugel C, Dela Vega T, Wong A, Brillantes B, Ciferri C, Dutina G, Lee G, Lehoux I, Li ZR, Lior-Hoffmann L, Hwang J, Lonergan C, Martin L, Mortara K, Nguyen L, Payandeh J, Perez A, Sampang J, Singh L, Schroeder K, Tam C, Ti S, Win YN, Bowman K.
Kraft E, et al. Among authors: brillantes b.
Methods Mol Biol. 2019;2025:51-68. doi: 10.1007/978-1-4939-9624-7_3.
Methods Mol Biol. 2019.
PMID: 31267448
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Structural basis for resistance to diverse classes of NAMPT inhibitors.
Wang W, Elkins K, Oh A, Ho YC, Wu J, Li H, Xiao Y, Kwong M, Coons M, Brillantes B, Cheng E, Crocker L, Dragovich PS, Sampath D, Zheng X, Bair KW, O'Brien T, Belmont LD.
Wang W, et al. Among authors: brillantes b.
PLoS One. 2014 Oct 6;9(10):e109366. doi: 10.1371/journal.pone.0109366. eCollection 2014.
PLoS One. 2014.
PMID: 25285661
Free PMC article.
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