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Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis.
Perry RJ, Zhang D, Guerra MT, Brill AL, Goedeke L, Nasiri AR, Rabin-Court A, Wang Y, Peng L, Dufour S, Zhang Y, Zhang XM, Butrico GM, Toussaint K, Nozaki Y, Cline GW, Petersen KF, Nathanson MH, Ehrlich BE, Shulman GI. Perry RJ, et al. Among authors: brill al. Nature. 2020 Mar;579(7798):279-283. doi: 10.1038/s41586-020-2074-6. Epub 2020 Mar 4. Nature. 2020. PMID: 32132708 Free PMC article.
Human Islet Expression Levels of Prostaglandin E2 Synthetic Enzymes, But Not Prostaglandin EP3 Receptor, Are Positively Correlated with Markers of β-Cell Function and Mass in Nondiabetic Obesity.
Truchan NA, Fenske RJ, Sandhu HK, Weeks AM, Patibandla C, Wancewicz B, Pabich S, Reuter A, Harrington JM, Brill AL, Peter DC, Nall R, Daniels M, Punt M, Kaiser CE, Cox ED, Ge Y, Davis DB, Kimple ME. Truchan NA, et al. Among authors: brill al. ACS Pharmacol Transl Sci. 2021 Jun 16;4(4):1338-1348. doi: 10.1021/acsptsci.1c00045. eCollection 2021 Aug 13. ACS Pharmacol Transl Sci. 2021. PMID: 34423270 Free PMC article.
Agonist-independent Gαz activity negatively regulates beta-cell compensation in a diet-induced obesity model of type 2 diabetes.
Schaid MD, Green CL, Peter DC, Gallagher SJ, Guthery E, Carbajal KA, Harrington JM, Kelly GM, Reuter A, Wehner ML, Brill AL, Neuman JC, Lamming DW, Kimple ME. Schaid MD, et al. Among authors: brill al. J Biol Chem. 2021 Jan-Jun;296:100056. doi: 10.1074/jbc.RA120.015585. Epub 2020 Nov 24. J Biol Chem. 2021. PMID: 33172888 Free PMC article.
17 results