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NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Gu M, Zhou X, Sohn JH, Zhu L, Jie Z, Yang JY, Zheng X, Xie X, Yang J, Shi Y, Brightbill HD, Kim JB, Wang J, Cheng X, Sun SC. Gu M, et al. Among authors: brightbill hd. Nat Immunol. 2021 Feb;22(2):193-204. doi: 10.1038/s41590-020-00829-6. Epub 2021 Jan 4. Nat Immunol. 2021. PMID: 33398181 Free PMC article.
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.
Brightbill HD, Suto E, Blaquiere N, Ramamoorthi N, Sujatha-Bhaskar S, Gogol EB, Castanedo GM, Jackson BT, Kwon YC, Haller S, Lesch J, Bents K, Everett C, Kohli PB, Linge S, Christian L, Barrett K, Jaochico A, Berezhkovskiy LM, Fan PW, Modrusan Z, Veliz K, Townsend MJ, DeVoss J, Johnson AR, Godemann R, Lee WP, Austin CD, McKenzie BS, Hackney JA, Crawford JJ, Staben ST, Alaoui Ismaili MH, Wu LC, Ghilardi N. Brightbill HD, et al. Nat Commun. 2018 Jan 12;9(1):179. doi: 10.1038/s41467-017-02672-0. Nat Commun. 2018. PMID: 29330524 Free PMC article.
A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production.
Simpson LJ, Patel S, Bhakta NR, Choy DF, Brightbill HD, Ren X, Wang Y, Pua HH, Baumjohann D, Montoya MM, Panduro M, Remedios KA, Huang X, Fahy JV, Arron JR, Woodruff PG, Ansel KM. Simpson LJ, et al. Among authors: brightbill hd. Nat Immunol. 2014 Dec;15(12):1162-70. doi: 10.1038/ni.3026. Epub 2014 Nov 2. Nat Immunol. 2014. PMID: 25362490 Free PMC article.
34 results