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Single and combination herpes simplex virus type 2 glycoprotein vaccines adjuvanted with CpG oligodeoxynucleotides or monophosphoryl lipid A exhibit differential immunity that is not correlated to protection in animal models.
Khodai T, Chappell D, Christy C, Cockle P, Eyles J, Hammond D, Gore K, McCluskie MJ, Evans DM, Lang S, Loudon PT, Townend T, Wright P, West K, Bright H. Khodai T, et al. Clin Vaccine Immunol. 2011 Oct;18(10):1702-9. doi: 10.1128/CVI.05071-11. Epub 2011 Aug 18. Clin Vaccine Immunol. 2011. PMID: 21852545 Free PMC article.
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