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Tyrosyl-DNA Phosphodiesterase I N-Terminal Domain Modifications and Interactions Regulate Cellular Function.
Genes (Basel). 2019 Nov 6;10(11):897. doi: 10.3390/genes10110897.
Genes (Basel). 2019.
PMID: 31698852
Free PMC article.
Review.
Targeting Tyrosyl-DNA phosphodiesterase I to enhance toxicity of phosphodiester linked DNA-adducts.
Brettrager EJ, van Waardenburg RCAM.
Brettrager EJ, et al.
Cancer Drug Resist. 2019;2(4):1153-1163. doi: 10.20517/cdr.2019.91. Epub 2019 Dec 19.
Cancer Drug Resist. 2019.
PMID: 31875206
Free PMC article.
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Sulfotransferase 4A1 activity facilitates sulfate-dependent cellular protection to oxidative stress.
Brettrager EJ, Meehan AW, Falany CN, van Waardenburg RCAM.
Brettrager EJ, et al.
Sci Rep. 2022 Jan 31;12(1):1625. doi: 10.1038/s41598-022-05582-4.
Sci Rep. 2022.
PMID: 35102205
Free PMC article.
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Conformational switching in the coiled-coil domains of a proteasomal ATPase regulates substrate processing.
Snoberger A, Brettrager EJ, Smith DM.
Snoberger A, et al. Among authors: brettrager ej.
Nat Commun. 2018 Jun 18;9(1):2374. doi: 10.1038/s41467-018-04731-6.
Nat Commun. 2018.
PMID: 29915197
Free PMC article.
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Zymolyase Treatment of Saccharomyces cerevisiae Affects Cellular Proteins and Degrades Tyrosyl-DNA Phosphodiesterase I.
Brettrager EJ, Frederick AJ, van Waardenburg RCAM.
Brettrager EJ, et al.
DNA Cell Biol. 2024 Apr 29. doi: 10.1089/dna.2024.0062. Online ahead of print.
DNA Cell Biol. 2024.
PMID: 38682313
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N-terminal domain of tyrosyl-DNA phosphodiesterase I regulates topoisomerase I-induced toxicity in cells.
Brettrager EJ, Cuya SM, Tibbs ZE, Zhang J, Falany CN, Aller SG, van Waardenburg RCAM.
Brettrager EJ, et al.
Sci Rep. 2023 Jan 25;13(1):1377. doi: 10.1038/s41598-023-28564-6.
Sci Rep. 2023.
PMID: 36697463
Free PMC article.
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