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mARC1 in MASLD: Modulation of lipid accumulation in human hepatocytes and adipocytes.
Jones AK, Bajrami B, Campbell MK, Erzurumluoglu AM, Guo Q, Chen H, Zhang X, Zeveleva S, Kvaskoff D, Brunner AD, Muller S, Gathey V, Dave RM, Tanner JW, Rixen S, Struwe MA, Phoenix K, Klumph KJ, Robinson H, Veyel D, Muller A, Noyvert B, Bartholdy BA, Steixner-Kumar AA, Stutzki J, Drichel D, Omland S, Sheehan R, Hill J, Bretschneider T, Gottschling D, Scheidig AJ, Clement B, Giera M, Ding Z, Broadwater J, Warren CR. Jones AK, et al. Among authors: bretschneider t. Hepatol Commun. 2024 Apr 12;8(5):e0365. doi: 10.1097/HC9.0000000000000365. eCollection 2024 May 1. Hepatol Commun. 2024. PMID: 38619429 Free PMC article.
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer.
Kuttruff CA, Fleck M, Carotta S, Arnhof H, Bretschneider T, Dahmann G, Gremel G, Grube A, Handschuh S, Heimann A, Hofmann MH, Impagnatiello MA, Nar H, Rast G, Schaaf O, Schmidt E, Oost T. Kuttruff CA, et al. Among authors: bretschneider t. J Med Chem. 2023 Jul 27;66(14):9376-9400. doi: 10.1021/acs.jmedchem.3c00510. Epub 2023 Jul 14. J Med Chem. 2023. PMID: 37450324
Formation and closure of macropinocytic cups in Dictyostelium.
Lutton JE, Coker HLE, Paschke P, Munn CJ, King JS, Bretschneider T, Kay RR. Lutton JE, et al. Among authors: bretschneider t. Curr Biol. 2023 Aug 7;33(15):3083-3096.e6. doi: 10.1016/j.cub.2023.06.017. Epub 2023 Jun 27. Curr Biol. 2023. PMID: 37379843 Free PMC article.
Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science.
Thamm S, Willwacher MK, Aspnes GE, Bretschneider T, Brown NF, Buschbom-Helmke S, Fox T, Gargano EM, Grabowski D, Hoenke C, Matera D, Mueck K, Peters S, Reindl S, Riether D, Schmid M, Tautermann CS, Teitelbaum AM, Trünkle C, Veser T, Winter M, Wortmann L. Thamm S, et al. Among authors: bretschneider t. J Med Chem. 2023 Feb 23;66(4):2832-2850. doi: 10.1021/acs.jmedchem.2c01884. Epub 2023 Feb 2. J Med Chem. 2023. PMID: 36727857 Free PMC article.
Differential analyte derivatization enables unbiased MALDI-TOF-based high-throughput screening: A proof-of-concept study for the discovery of catechol-o-methyltransferase inhibitors.
Winter M, Simon RP, Wang Y, Bretschneider T, Bauer M, Magarkar A, Reindl W, Fernández-Montalván A, Montel F, Büttner FH. Winter M, et al. Among authors: bretschneider t. SLAS Discov. 2022 Jul;27(5):287-297. doi: 10.1016/j.slasd.2022.05.002. Epub 2022 May 18. SLAS Discov. 2022. PMID: 35597517 Free article.
Effects of GPR139 agonism on effort expenditure for food reward in rodent models: Evidence for pro-motivational actions.
Münster A, Sommer S, Kúkeľová D, Sigrist H, Koros E, Deiana S, Klinder K, Baader-Pagler T, Mayer-Wrangowski S, Ferger B, Bretschneider T, Pryce CR, Hauber W, von Heimendahl M. Münster A, et al. Among authors: bretschneider t. Neuropharmacology. 2022 Aug 1;213:109078. doi: 10.1016/j.neuropharm.2022.109078. Epub 2022 May 10. Neuropharmacology. 2022. PMID: 35561791 Free article.
The Amoebal Model for Macropinocytosis.
Kay RR, Lutton J, Coker H, Paschke P, King JS, Bretschneider T. Kay RR, et al. Among authors: bretschneider t. Subcell Biochem. 2022;98:41-59. doi: 10.1007/978-3-030-94004-1_3. Subcell Biochem. 2022. PMID: 35378702
108 results