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The use of cell-delivered gene therapy for the treatment of HIV/AIDS.
Immunol Res. 2010 Dec;48(1-3):84-98. doi: 10.1007/s12026-010-8169-7.
Immunol Res. 2010.
PMID: 20737298
Review.
CCR5 as a natural and modulated target for inhibition of HIV.
Burke BP, Boyd MP, Impey H, Breton LR, Bartlett JS, Symonds GP, Hütter G.
Burke BP, et al. Among authors: breton lr.
Viruses. 2013 Dec 30;6(1):54-68. doi: 10.3390/v6010054.
Viruses. 2013.
PMID: 24381033
Free PMC article.
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Preclinical safety and efficacy of an anti-HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor.
Wolstein O, Boyd M, Millington M, Impey H, Boyer J, Howe A, Delebecque F, Cornetta K, Rothe M, Baum C, Nicolson T, Koldej R, Zhang J, Keech N, Camba Colón J, Breton L, Bartlett J, An DS, Chen IS, Burke B, Symonds GP.
Wolstein O, et al.
Mol Ther Methods Clin Dev. 2014 Feb 12;1:11. doi: 10.1038/mtm.2013.11. eCollection 2014.
Mol Ther Methods Clin Dev. 2014.
PMID: 26015947
Free PMC article.
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Cell-Delivered Entry Inhibitors for HIV-1: CCR5 Downregulation and Blocking Virus/Membrane Fusion in Defending the Host Cell Population.
Symonds G, Bartlett JS, Kiem HP, Tsie M, Breton L.
Symonds G, et al.
AIDS Patient Care STDS. 2016 Dec;30(12):545-550. doi: 10.1089/apc.2016.0245.
AIDS Patient Care STDS. 2016.
PMID: 27905841
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Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector.
Burke BP, Levin BR, Zhang J, Sahakyan A, Boyer J, Carroll MV, Colón JC, Keech N, Rezek V, Bristol G, Eggers E, Cortado R, Boyd MP, Impey H, Shimizu S, Lowe EL, Ringpis GE, Kim SG, Vatakis DN, Breton LR, Bartlett JS, Chen IS, Kitchen SG, An DS, Symonds GP.
Burke BP, et al. Among authors: breton lr.
Mol Ther Nucleic Acids. 2015 Apr 14;4:e236. doi: 10.1038/mtna.2015.10.
Mol Ther Nucleic Acids. 2015.
PMID: 25872029
Free article.
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