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Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.
Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM. Erami Z, et al. Among authors: bresnick ar. Biochem J. 2017 Nov 16;474(23):3903-3914. doi: 10.1042/BCJ20170279. Biochem J. 2017. PMID: 29046393 Free PMC article.
GPCR Signaling Mediates Tumor Metastasis via PI3Kβ.
Khalil BD, Hsueh C, Cao Y, Abi Saab WF, Wang Y, Condeelis JS, Bresnick AR, Backer JM. Khalil BD, et al. Among authors: bresnick ar. Cancer Res. 2016 May 15;76(10):2944-53. doi: 10.1158/0008-5472.CAN-15-1675. Epub 2016 Mar 24. Cancer Res. 2016. PMID: 27013201 Free PMC article.
A single discrete Rab5-binding site in phosphoinositide 3-kinase β is required for tumor cell invasion.
Heitz SD, Hamelin DJ, Hoffmann RM, Greenberg N, Salloum G, Erami Z, Khalil BD, Shymanets A, Steidle EA, Gong GQ, Nürnberg B, Burke JE, Flanagan JU, Bresnick AR, Backer JM. Heitz SD, et al. Among authors: bresnick ar. J Biol Chem. 2019 Mar 22;294(12):4621-4633. doi: 10.1074/jbc.RA118.006032. Epub 2019 Jan 18. J Biol Chem. 2019. PMID: 30659094 Free PMC article.
G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness.
Dbouk HA, Vadas O, Shymanets A, Burke JE, Salamon RS, Khalil BD, Barrett MO, Waldo GL, Surve C, Hsueh C, Perisic O, Harteneck C, Shepherd PR, Harden TK, Smrcka AV, Taussig R, Bresnick AR, Nürnberg B, Williams RL, Backer JM. Dbouk HA, et al. Among authors: bresnick ar. Sci Signal. 2012 Dec 4;5(253):ra89. doi: 10.1126/scisignal.2003264. Sci Signal. 2012. PMID: 23211529 Free PMC article.
Fyn phosphorylates human MAP-2c on tyrosine 67.
Zamora-Leon SP, Bresnick A, Backer JM, Shafit-Zagardo B. Zamora-Leon SP, et al. J Biol Chem. 2005 Jan 21;280(3):1962-70. doi: 10.1074/jbc.M411380200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536091 Free article.
PIP3 abundance overcomes PI3K signaling selectivity in invadopodia.
Jakubik CT, Weckerly CC, Hammond GRV, Bresnick AR, Backer JM. Jakubik CT, et al. Among authors: bresnick ar. FEBS Lett. 2022 Feb;596(4):417-426. doi: 10.1002/1873-3468.14273. Epub 2022 Jan 12. FEBS Lett. 2022. PMID: 34990021 Free PMC article.
86 results