Brenton JD - Search Results

1

Complex stiffness gradient substrates for studying mechanotactic cell migration.

Kuo CH, Xian J, Brenton JD, Franze K, Sivaniah E. Kuo CH, et al. Among authors: brenton jd. Adv Mater. 2012 Nov 27;24(45):6059-64. doi: 10.1002/adma.201202520. Epub 2012 Sep 18. Adv Mater. 2012. PMID: 22991224

2

The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling.

Wang F, Hu W, Xian J, Ohnuma S, Brenton JD. Wang F, et al. Among authors: brenton jd. Dev Biol. 2013 Jul 1;379(1):16-27. doi: 10.1016/j.ydbio.2012.11.010. Epub 2012 Dec 13. Dev Biol. 2013. PMID: 23246513 Free article.

3

The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer.

Ng CK, Cooke SL, Howe K, Newman S, Xian J, Temple J, Batty EM, Pole JC, Langdon SP, Edwards PA, Brenton JD. Ng CK, et al. Among authors: brenton jd. J Pathol. 2012 Apr;226(5):703-12. doi: 10.1002/path.3980. Epub 2012 Feb 9. J Pathol. 2012. PMID: 22183581

4

A-ring dihalogenation increases the cellular activity of combretastatin-templated tetrazoles.

Beale TM, Allwood DM, Bender A, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM, Shearman JW, Temple J, Unger J, Watts CA, Xian J. Beale TM, et al. Among authors: brenton jd. ACS Med Chem Lett. 2012 Jan 19;3(3):177-81. doi: 10.1021/ml200149g. eCollection 2012 Mar 8. ACS Med Chem Lett. 2012. PMID: 24900453 Free PMC article.

5

Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier.

Martins FC, Santiago Id, Trinh A, Xian J, Guo A, Sayal K, Jimenez-Linan M, Deen S, Driver K, Mack M, Aslop J, Pharoah PD, Markowetz F, Brenton JD. Martins FC, et al. Among authors: brenton jd. Genome Biol. 2014 Dec 17;15(12):526. doi: 10.1186/s13059-014-0526-8. Genome Biol. 2014. PMID: 25608477 Free PMC article.

6

Evolution of platinum resistance in high-grade serous ovarian cancer.

Cooke SL, Brenton JD. Cooke SL, et al. Among authors: brenton jd. Lancet Oncol. 2011 Nov;12(12):1169-74. doi: 10.1016/S1470-2045(11)70123-1. Lancet Oncol. 2011. PMID: 21742554

7

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.

Ahmed AA, Etemadmoghadam D, Temple J, Lynch AG, Riad M, Sharma R, Stewart C, Fereday S, Caldas C, Defazio A, Bowtell D, Brenton JD. Ahmed AA, et al. Among authors: brenton jd. J Pathol. 2010 May;221(1):49-56. doi: 10.1002/path.2696. J Pathol. 2010. PMID: 20229506 Free PMC article.

8

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes.

McBride DJ, Etemadmoghadam D, Cooke SL, Alsop K, George J, Butler A, Cho J, Galappaththige D, Greenman C, Howarth KD, Lau KW, Ng CK, Raine K, Teague J, Wedge DC, Cancer Study Group AO, Caubit X, Stratton MR, Brenton JD, Campbell PJ, Futreal PA, Bowtell DD. McBride DJ, et al. Among authors: brenton jd. J Pathol. 2012 Aug;227(4):446-55. doi: 10.1002/path.4042. Epub 2012 Jul 2. J Pathol. 2012. PMID: 22514011 Free PMC article.

9

Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.

Schwarz RF, Ng CK, Cooke SL, Newman S, Temple J, Piskorz AM, Gale D, Sayal K, Murtaza M, Baldwin PJ, Rosenfeld N, Earl HM, Sala E, Jimenez-Linan M, Parkinson CA, Markowetz F, Brenton JD. Schwarz RF, et al. Among authors: brenton jd. PLoS Med. 2015 Feb 24;12(2):e1001789. doi: 10.1371/journal.pmed.1001789. eCollection 2015 Feb. PLoS Med. 2015. PMID: 25710373 Free PMC article.

10

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.

Cooke SL, Ng CK, Melnyk N, Garcia MJ, Hardcastle T, Temple J, Langdon S, Huntsman D, Brenton JD. Cooke SL, et al. Among authors: brenton jd. Oncogene. 2010 Sep 2;29(35):4905-13. doi: 10.1038/onc.2010.245. Epub 2010 Jun 28. Oncogene. 2010. PMID: 20581869 Free PMC article.

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