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Neuronal impact of patient-specific aberrant NRXN1α splicing.
Flaherty E, Zhu S, Barretto N, Cheng E, Deans PJM, Fernando MB, Schrode N, Francoeur N, Antoine A, Alganem K, Halpern M, Deikus G, Shah H, Fitzgerald M, Ladran I, Gochman P, Rapoport J, Tsankova NM, McCullumsmith R, Hoffman GE, Sebra R, Fang G, Brennand KJ. Flaherty E, et al. Among authors: brennand kj. Nat Genet. 2019 Dec;51(12):1679-1690. doi: 10.1038/s41588-019-0539-z. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784728 Free PMC article.
Neural stem and progenitor cells in health and disease.
Ladran I, Tran N, Topol A, Brennand KJ. Ladran I, et al. Among authors: brennand kj. Wiley Interdiscip Rev Syst Biol Med. 2013 Nov-Dec;5(6):701-15. doi: 10.1002/wsbm.1239. Epub 2013 Sep 20. Wiley Interdiscip Rev Syst Biol Med. 2013. PMID: 24068527 Free PMC article. Review.
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.
Brennand K, Savas JN, Kim Y, Tran N, Simone A, Hashimoto-Torii K, Beaumont KG, Kim HJ, Topol A, Ladran I, Abdelrahim M, Matikainen-Ankney B, Chao SH, Mrksich M, Rakic P, Fang G, Zhang B, Yates JR 3rd, Gage FH. Brennand K, et al. Mol Psychiatry. 2015 Mar;20(3):361-8. doi: 10.1038/mp.2014.22. Epub 2014 Apr 1. Mol Psychiatry. 2015. PMID: 24686136 Free PMC article.
Dopaminergic differentiation of schizophrenia hiPSCs.
Hartley BJ, Tran N, Ladran I, Reggio K, Brennand KJ. Hartley BJ, et al. Among authors: brennand kj. Mol Psychiatry. 2015 May;20(5):549-50. doi: 10.1038/mp.2014.194. Epub 2015 Jan 27. Mol Psychiatry. 2015. PMID: 25623947 Free PMC article. No abstract available.
Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.
Topol A, English JA, Flaherty E, Rajarajan P, Hartley BJ, Gupta S, Desland F, Zhu S, Goff T, Friedman L, Rapoport J, Felsenfeld D, Cagney G, Mackay-Sim A, Savas JN, Aronow B, Fang G, Zhang B, Cotter D, Brennand KJ. Topol A, et al. Among authors: brennand kj. Transl Psychiatry. 2015 Oct 20;5(10):e662. doi: 10.1038/tp.2015.118. Transl Psychiatry. 2015. PMID: 26485546 Free PMC article.
Differential responses to lithium in hyperexcitable neurons from patients with bipolar disorder.
Mertens J, Wang QW, Kim Y, Yu DX, Pham S, Yang B, Zheng Y, Diffenderfer KE, Zhang J, Soltani S, Eames T, Schafer ST, Boyer L, Marchetto MC, Nurnberger JI, Calabrese JR, Ødegaard KJ, McCarthy MJ, Zandi PP, Alda M, Nievergelt CM; Pharmacogenomics of Bipolar Disorder Study; Mi S, Brennand KJ, Kelsoe JR, Gage FH, Yao J. Mertens J, et al. Among authors: brennand kj. Nature. 2015 Nov 5;527(7576):95-9. doi: 10.1038/nature15526. Epub 2015 Oct 28. Nature. 2015. PMID: 26524527 Free PMC article.
145 results