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CD4 T cells are rapidly depleted from tuberculosis granulomas following acute SIV co-infection.
Foreman TW, Nelson CE, Kauffman KD, Lora NE, Vinhaes CL, Dorosky DE, Sakai S, Gomez F, Fleegle JD, Parham M, Perera SR, Lindestam Arlehamn CS, Sette A; Tuberculosis Imaging Program; Brenchley JM, Queiroz ATL, Andrade BB, Kabat J, Via LE, Barber DL. Foreman TW, et al. Among authors: brenchley jm. Cell Rep. 2022 May 31;39(9):110896. doi: 10.1016/j.celrep.2022.110896. Cell Rep. 2022. PMID: 35649361 Free article.
T cell receptor recognition motifs govern immune escape patterns in acute SIV infection.
Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, Ambrozak DR, Edghill-Smith Y, Kuroda MJ, Bogdan D, Kunstman K, Letvin NL, Franchini G, Wolinsky SM, Koup RA, Douek DC. Price DA, et al. Among authors: brenchley jm. Immunity. 2004 Dec;21(6):793-803. doi: 10.1016/j.immuni.2004.10.010. Immunity. 2004. PMID: 15589168 Free article.
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. Brenchley JM, et al. Nat Med. 2006 Dec;12(12):1365-71. doi: 10.1038/nm1511. Epub 2006 Nov 19. Nat Med. 2006. PMID: 17115046
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.
Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M Jr, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ. Okoye A, et al. Among authors: brenchley jm. J Exp Med. 2007 Sep 3;204(9):2171-85. doi: 10.1084/jem.20070567. Epub 2007 Aug 27. J Exp Med. 2007. PMID: 17724130 Free PMC article.
Initiation of antiretroviral therapy 48 hours after infection with simian immunodeficiency virus potently suppresses acute-phase viremia and blocks the massive loss of memory CD4+ T cells but fails to prevent disease.
Kubo M, Nishimura Y, Shingai M, Lee W, Brenchley J, Lafont B, Buckler-White A, Igarashi T, Martin MA. Kubo M, et al. J Virol. 2009 Jul;83(14):7099-108. doi: 10.1128/JVI.02522-08. Epub 2009 May 6. J Virol. 2009. PMID: 19420078 Free PMC article.
199 results