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p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1.
Nat Commun. 2018 Aug 24;9(1):3432. doi: 10.1038/s41467-018-05711-6.
Nat Commun. 2018.
PMID: 30143607
Free PMC article.
Hypothalamic UDP Increases in Obesity and Promotes Feeding via P2Y6-Dependent Activation of AgRP Neurons.
Steculorum SM, Paeger L, Bremser S, Evers N, Hinze Y, Idzko M, Kloppenburg P, Brüning JC.
Steculorum SM, et al. Among authors: bremser s.
Cell. 2015 Sep 10;162(6):1404-17. doi: 10.1016/j.cell.2015.08.032.
Cell. 2015.
PMID: 26359991
Free article.
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AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue.
Steculorum SM, Ruud J, Karakasilioti I, Backes H, Engström Ruud L, Timper K, Hess ME, Tsaousidou E, Mauer J, Vogt MC, Paeger L, Bremser S, Klein AC, Morgan DA, Frommolt P, Brinkkötter PT, Hammerschmidt P, Benzing T, Rahmouni K, Wunderlich FT, Kloppenburg P, Brüning JC.
Steculorum SM, et al. Among authors: bremser s.
Cell. 2016 Mar 24;165(1):125-138. doi: 10.1016/j.cell.2016.02.044.
Cell. 2016.
PMID: 27015310
Free PMC article.
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Inhibition of P2Y6 Signaling in AgRP Neurons Reduces Food Intake and Improves Systemic Insulin Sensitivity in Obesity.
Steculorum SM, Timper K, Engström Ruud L, Evers N, Paeger L, Bremser S, Kloppenburg P, Brüning JC.
Steculorum SM, et al. Among authors: bremser s.
Cell Rep. 2017 Feb 14;18(7):1587-1597. doi: 10.1016/j.celrep.2017.01.047.
Cell Rep. 2017.
PMID: 28199831
Free article.
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PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding.
Jais A, Paeger L, Sotelo-Hitschfeld T, Bremser S, Prinzensteiner M, Klemm P, Mykytiuk V, Widdershooven PJM, Vesting AJ, Grzelka K, Minère M, Cremer AL, Xu J, Korotkova T, Lowell BB, Zeilhofer HU, Backes H, Fenselau H, Wunderlich FT, Kloppenburg P, Brüning JC.
Jais A, et al. Among authors: bremser s.
Neuron. 2020 Jun 17;106(6):1009-1025.e10. doi: 10.1016/j.neuron.2020.03.022. Epub 2020 Apr 16.
Neuron. 2020.
PMID: 32302532
Free PMC article.
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GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function.
Timper K, Del Río-Martín A, Cremer AL, Bremser S, Alber J, Giavalisco P, Varela L, Heilinger C, Nolte H, Trifunovic A, Horvath TL, Kloppenburg P, Backes H, Brüning JC.
Timper K, et al. Among authors: bremser s.
Cell Metab. 2020 Jun 2;31(6):1189-1205.e13. doi: 10.1016/j.cmet.2020.05.001. Epub 2020 May 19.
Cell Metab. 2020.
PMID: 32433922
Free PMC article.
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Hypothalamic Pomc Neurons Innervate the Spinal Cord and Modulate the Excitability of Premotor Circuits.
Reinoß P, Ciglieri E, Minére M, Bremser S, Klein A, Löhr H, Fuller PM, Büschges A, Kloppenburg P, Fenselau H, Hammerschmidt M.
Reinoß P, et al. Among authors: bremser s.
Curr Biol. 2020 Dec 7;30(23):4579-4593.e7. doi: 10.1016/j.cub.2020.08.103. Epub 2020 Sep 24.
Curr Biol. 2020.
PMID: 32976803
Free PMC article.
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