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Alpha synuclein post translational modifications: potential targets for Parkinson's disease therapy?
Front Mol Neurosci. 2023 May 25;16:1197853. doi: 10.3389/fnmol.2023.1197853. eCollection 2023.
Front Mol Neurosci. 2023.
PMID: 37305556
Free PMC article.
Review.
The good and bad of therapeutic strategies that directly target α-synuclein.
Longhena F, Faustini G, Brembati V, Pizzi M, Bellucci A.
Longhena F, et al. Among authors: brembati v.
IUBMB Life. 2020 Apr;72(4):590-600. doi: 10.1002/iub.2194. Epub 2019 Nov 6.
IUBMB Life. 2020.
PMID: 31693290
Free article.
Review.
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An updated reappraisal of synapsins: structure, function and role in neurological and psychiatric disorders.
Longhena F, Faustini G, Brembati V, Pizzi M, Benfenati F, Bellucci A.
Longhena F, et al. Among authors: brembati v.
Neurosci Biobehav Rev. 2021 Nov;130:33-60. doi: 10.1016/j.neubiorev.2021.08.011. Epub 2021 Aug 15.
Neurosci Biobehav Rev. 2021.
PMID: 34407457
Review.
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Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype.
Faustini G, Longhena F, Masato A, Bassareo V, Frau R, Klingstedt T, Shirani H, Brembati V, Parrella E, Vezzoli M, Nilsson KPR, Pizzi M, Spillantini MG, Bubacco L, Bellucci A.
Faustini G, et al. Among authors: brembati v.
Mol Ther. 2022 Apr 6;30(4):1465-1483. doi: 10.1016/j.ymthe.2022.01.021. Epub 2022 Jan 14.
Mol Ther. 2022.
PMID: 35038583
Free PMC article.
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Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson's Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice.
Casiraghi A, Longhena F, Faustini G, Ribaudo G, Suigo L, Camacho-Hernandez GA, Bono F, Brembati V, Newman AH, Gianoncelli A, Straniero V, Bellucci A, Valoti E.
Casiraghi A, et al. Among authors: brembati v.
Pharmaceutics. 2022 Jul 30;14(8):1595. doi: 10.3390/pharmaceutics14081595.
Pharmaceutics. 2022.
PMID: 36015221
Free PMC article.
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Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson's Disease.
Brembati V, Faustini G, Longhena F, Outeiro TF, Bellucci A.
Brembati V, et al.
Int J Mol Sci. 2023 Aug 30;24(17):13435. doi: 10.3390/ijms241713435.
Int J Mol Sci. 2023.
PMID: 37686236
Free PMC article.
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Distinct alpha-Synuclein species induced by seeding are selectively cleared by the Lysosome or the Proteasome in neuronally differentiated SH-SY5Y cells.
Pantazopoulou M, Brembati V, Kanellidi A, Bousset L, Melki R, Stefanis L.
Pantazopoulou M, et al. Among authors: brembati v.
J Neurochem. 2021 Mar;156(6):880-896. doi: 10.1111/jnc.15174. Epub 2020 Sep 22.
J Neurochem. 2021.
PMID: 32869336
Free article.
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