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Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC. Magalhaes Moreira DR, et al. Eur J Med Chem. 2014 Mar 21;75:467-78. doi: 10.1016/j.ejmech.2014.02.001. Epub 2014 Feb 3. Eur J Med Chem. 2014. PMID: 24561675
Leishmaniases diagnosis: an update on the use of immunological and molecular tools.
de Paiva-Cavalcanti M, de Morais RC, Pessoa-E-Silva R, Trajano-Silva LA, Gonçalves-de-Albuquerque Sda C, Tavares Dde H, Brelaz-de-Castro MC, Silva Rde F, Pereira VR. de Paiva-Cavalcanti M, et al. Cell Biosci. 2015 Jun 17;5:31. doi: 10.1186/s13578-015-0021-2. eCollection 2015. Cell Biosci. 2015. PMID: 26097678 Free PMC article.
Combination of flow cytometry and qPCR to study the immune response of american cutaneous leishmaniasis patients.
Brelaz-de-Castro MCA, de Almeida TM, de Almeida AF, de Assis Souza M, de Oliveira Mendes AP, Silva RFE, de Brito MEF, Pereira VRA. Brelaz-de-Castro MCA, et al. Among authors: de brito mef, de almeida tm, de oliveira mendes ap, de almeida af, de assis souza m. Microb Pathog. 2018 Oct;123:433-439. doi: 10.1016/j.micpath.2018.07.044. Epub 2018 Aug 1. Microb Pathog. 2018. PMID: 30076983 Free article.
Chagas Disease Treatment and Rational Drug Discovery: A Challenge That Remains.
Silva ACC, Brelaz-de-Castro MCA, Leite ACL, Pereira VRA, Hernandes MZ. Silva ACC, et al. Among authors: brelaz de castro mca. Front Pharmacol. 2019 Aug 2;10:873. doi: 10.3389/fphar.2019.00873. eCollection 2019. Front Pharmacol. 2019. PMID: 31427977 Free PMC article. No abstract available.
IL-1 family and Cutaneous Leishmaniasis: A poorly understood relationship.
Amorim EADS, de França ÁA, Pereira VRA, Brelaz-de-Castro MCA. Amorim EADS, et al. Among authors: brelaz de castro mca. Cytokine Growth Factor Rev. 2021 Feb;57:85-92. doi: 10.1016/j.cytogfr.2020.06.007. Epub 2020 Jun 8. Cytokine Growth Factor Rev. 2021. PMID: 32540132
Chagas disease: Immunology of the disease at a glance.
Cristovão-Silva AC, Brelaz-de-Castro MCA, Hernandes MZ, Pereira VRA. Cristovão-Silva AC, et al. Among authors: brelaz de castro mca. Cytokine Growth Factor Rev. 2021 Dec;62:15-22. doi: 10.1016/j.cytogfr.2021.10.001. Epub 2021 Oct 13. Cytokine Growth Factor Rev. 2021. PMID: 34696979 Review.
Opinion Article: NK Cells in Cutaneous Leishmaniasis: Protection or Damage?
Cavalcante MKA, de Freitas E Silva R, Pereira VRA, Brelaz-de-Castro MCA. Cavalcante MKA, et al. Among authors: brelaz de castro mca. Front Immunol. 2022 Jul 1;13:933490. doi: 10.3389/fimmu.2022.933490. eCollection 2022. Front Immunol. 2022. PMID: 35844579 Free PMC article. No abstract available.
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