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Rediscovery of natural products using genomic tools.
Bioorg Med Chem Lett. 2006 Jun 1;16(11):2846-9. doi: 10.1016/j.bmcl.2006.03.022. Epub 2006 Mar 31.
Bioorg Med Chem Lett. 2006.
PMID: 16580203
A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation.
Brekman A, Singh KE, Polotskaia A, Kundu N, Bargonetti J.
Brekman A, et al.
Breast Cancer Res. 2011 Jan 11;13(1):R3. doi: 10.1186/bcr2804.
Breast Cancer Res. 2011.
PMID: 21223569
Free PMC article.
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Disruption of the p53-Mdm2 complex by Nutlin-3 reveals different cancer cell phenotypes.
Arva NC, Talbott KE, Okoro DR, Brekman A, Qiu WG, Bargonetti J.
Arva NC, et al. Among authors: brekman a.
Ethn Dis. 2008 Spring;18(2 Suppl 2):S2-1-8.
Ethn Dis. 2008.
PMID: 18646312
Free PMC article.
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Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathway.
Kundu N, Brekman A, Kim JY, Xiao G, Gao C, Bargonetti J.
Kundu N, et al. Among authors: brekman a.
Oncotarget. 2017 Jul 18;8(29):47916-47930. doi: 10.18632/oncotarget.18147.
Oncotarget. 2017.
PMID: 28615518
Free PMC article.
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DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1.
Boamah EK, Brekman A, Tomasz M, Myeku N, Figueiredo-Pereira M, Hunter S, Meyer J, Bhosle RC, Bargonetti J.
Boamah EK, et al. Among authors: brekman a.
Chem Res Toxicol. 2010 Jul 19;23(7):1151-62. doi: 10.1021/tx900420k.
Chem Res Toxicol. 2010.
PMID: 20536192
Free PMC article.
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EGF shifts human airway basal cell fate toward a smoking-associated airway epithelial phenotype.
Shaykhiev R, Zuo WL, Chao I, Fukui T, Witover B, Brekman A, Crystal RG.
Shaykhiev R, et al. Among authors: brekman a.
Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12102-7. doi: 10.1073/pnas.1303058110. Epub 2013 Jul 1.
Proc Natl Acad Sci U S A. 2013.
PMID: 23818594
Free PMC article.
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FOXJ1 prevents cilia growth inhibition by cigarette smoke in human airway epithelium in vitro.
Brekman A, Walters MS, Tilley AE, Crystal RG.
Brekman A, et al.
Am J Respir Cell Mol Biol. 2014 Nov;51(5):688-700. doi: 10.1165/rcmb.2013-0363OC.
Am J Respir Cell Mol Biol. 2014.
PMID: 24828273
Free PMC article.
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POU2AF1 Functions in the Human Airway Epithelium To Regulate Expression of Host Defense Genes.
Zhou H, Brekman A, Zuo WL, Ou X, Shaykhiev R, Agosto-Perez FJ, Wang R, Walters MS, Salit J, Strulovici-Barel Y, Staudt MR, Kaner RJ, Mezey JG, Crystal RG, Wang G.
Zhou H, et al. Among authors: brekman a.
J Immunol. 2016 Apr 1;196(7):3159-67. doi: 10.4049/jimmunol.1502400. Epub 2016 Feb 29.
J Immunol. 2016.
PMID: 26927796
Free PMC article.
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