Brekken RA - Search Results

1

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.

Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Among authors: brekken ra. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.

2

The acellular fraction of stored platelets promotes tumor cell invasion.

Dineen SP, Roland CL, Toombs JE, Kelher M, Silliman CC, Brekken RA, Barnett CC Jr. Dineen SP, et al. Among authors: brekken ra. J Surg Res. 2009 May 1;153(1):132-7. doi: 10.1016/j.jss.2008.04.013. Epub 2008 May 7. J Surg Res. 2009. PMID: 18541268

3

Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells.

Castro-Rivera E, Ran S, Brekken RA, Minna JD. Castro-Rivera E, et al. Among authors: brekken ra. Cancer Res. 2008 Oct 15;68(20):8295-303. doi: 10.1158/0008-5472.CAN-07-6601. Cancer Res. 2008. PMID: 18922901 Free PMC article.

4

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.

Soh J, Okumura N, Lockwood WW, Yamamoto H, Shigematsu H, Zhang W, Chari R, Shames DS, Tang X, MacAulay C, Varella-Garcia M, Vooder T, Wistuba II, Lam S, Brekken R, Toyooka S, Minna JD, Lam WL, Gazdar AF. Soh J, et al. PLoS One. 2009 Oct 14;4(10):e7464. doi: 10.1371/journal.pone.0007464. PLoS One. 2009. PMID: 19826477 Free PMC article.

5

Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer.

Roland CL, Lynn KD, Toombs JE, Dineen SP, Udugamasooriya DG, Brekken RA. Roland CL, et al. Among authors: brekken ra. PLoS One. 2009 Nov 3;4(11):e7669. doi: 10.1371/journal.pone.0007669. PLoS One. 2009. PMID: 19888452 Free PMC article.

6

Smac mimetic increases chemotherapy response and improves survival in mice with pancreatic cancer.

Dineen SP, Roland CL, Greer R, Carbon JG, Toombs JE, Gupta P, Bardeesy N, Sun H, Williams N, Minna JD, Brekken RA. Dineen SP, et al. Among authors: brekken ra. Cancer Res. 2010 Apr 1;70(7):2852-61. doi: 10.1158/0008-5472.CAN-09-3892. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332237 Free PMC article.

7

Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts.

Roland CL, Dineen SP, Toombs JE, Carbon JG, Smith CW, Brekken RA, Barnett CC Jr. Roland CL, et al. Among authors: brekken ra. Exp Biol Med (Maywood). 2010 Feb;235(2):263-70. doi: 10.1258/ebm.2009.009215. Exp Biol Med (Maywood). 2010. PMID: 20404043

8

r84, a novel therapeutic antibody against mouse and human VEGF with potent anti-tumor activity and limited toxicity induction.

Sullivan LA, Carbon JG, Roland CL, Toombs JE, Nyquist-Andersen M, Kavlie A, Schlunegger K, Richardson JA, Brekken RA. Sullivan LA, et al. Among authors: brekken ra. PLoS One. 2010 Aug 6;5(8):e12031. doi: 10.1371/journal.pone.0012031. PLoS One. 2010. PMID: 20700512 Free PMC article.

9

Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer.

Awasthi N, Kirane A, Schwarz MA, Toombs JE, Brekken RA, Schwarz RE. Awasthi N, et al. Among authors: brekken ra. BMC Cancer. 2011 Jan 12;11:15. doi: 10.1186/1471-2407-11-15. BMC Cancer. 2011. PMID: 21226944 Free PMC article.

10

TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation.

Ou YH, Torres M, Ram R, Formstecher E, Roland C, Cheng T, Brekken R, Wurz R, Tasker A, Polverino T, Tan SL, White MA. Ou YH, et al. Mol Cell. 2011 Feb 18;41(4):458-70. doi: 10.1016/j.molcel.2011.01.019. Mol Cell. 2011. PMID: 21329883 Free PMC article.

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