Breidenbach L - Search Results

1

A genetically modified minipig model for Alzheimer's disease with SORL1 haploinsufficiency.

Andersen OM, Bøgh N, Landau AM, Pløen GG, Jensen AMG, Monti G, Ulhøi BP, Nyengaard JR, Jacobsen KR, Jørgensen MM, Holm IE, Kristensen ML, Alstrup AKO, Hansen ESS, Teunissen CE, Breidenbach L, Droescher M, Liu Y, Pedersen HS, Callesen H, Luo Y, Bolund L, Brooks DJ, Laustsen C, Small SA, Mikkelsen LF, Sørensen CB. Andersen OM, et al. Among authors: breidenbach l. Cell Rep Med. 2022 Sep 20;3(9):100740. doi: 10.1016/j.xcrm.2022.100740. Epub 2022 Sep 12. Cell Rep Med. 2022. PMID: 36099918 Free PMC article.

2

Refinement of the rodent pentylenetetrazole proconvulsion assay, which is a good predictor of convulsions in repeat-dose toxicology studies.

Breidenbach L, Hempel K, Mittelstadt SW, Lynch JJ 3rd. Breidenbach L, et al. J Pharmacol Toxicol Methods. 2020 Jan-Feb;101:106653. doi: 10.1016/j.vascn.2019.106653. Epub 2019 Nov 12. J Pharmacol Toxicol Methods. 2020. PMID: 31730935

3

Measuring drug absorption improves interpretation of behavioral responses in a larval zebrafish locomotor assay for predicting seizure liability.

Cassar S, Breidenbach L, Olson A, Huang X, Britton H, Woody C, Sancheti P, Stolarik D, Wicke K, Hempel K, LeRoy B. Cassar S, et al. Among authors: breidenbach l. J Pharmacol Toxicol Methods. 2017 Nov;88(Pt 1):56-63. doi: 10.1016/j.vascn.2017.07.002. Epub 2017 Jul 13. J Pharmacol Toxicol Methods. 2017. PMID: 28712933

4

Exploratory EEG studies for the assessment of neurological liabilities in conscious dogs in early drug development.

Breidenbach L, Potschka H, Hempel K. Breidenbach L, et al. J Pharmacol Toxicol Methods. 2019 Jul-Aug;98:106581. doi: 10.1016/j.vascn.2019.106581. Epub 2019 May 15. J Pharmacol Toxicol Methods. 2019. PMID: 31102738

5

Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.

DaSilva JK, Breidenbach L, Deats T, Li D, Treinen K, Dinklo T, Kervyn S, Teuns G, Traebert M, Hempel K. DaSilva JK, et al. Among authors: breidenbach l. J Pharmacol Toxicol Methods. 2020 May-Jun;103:106683. doi: 10.1016/j.vascn.2020.106683. Epub 2020 Feb 24. J Pharmacol Toxicol Methods. 2020. PMID: 32105757

6

Reprint of: Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.

DaSilva JK, Breidenbach L, Deats T, Li D, Treinen K, Dinklo T, Kervyn S, Teuns G, Traebert M, Hempel K. DaSilva JK, et al. Among authors: breidenbach l. J Pharmacol Toxicol Methods. 2020 Sep;105:106919. doi: 10.1016/j.vascn.2020.106919. Epub 2020 Sep 30. J Pharmacol Toxicol Methods. 2020. PMID: 33011055

7

Monitoring metal patterns from urban and agrarian sites using the bumblebee Bombus terrestris as a bioindicator.

Breidenbach LR, Benner L, Roß-Nickoll M, Linnemann V, Schäffer A. Breidenbach LR, et al. Environ Sci Pollut Res Int. 2023 Dec;30(57):119947-119960. doi: 10.1007/s11356-023-30504-w. Epub 2023 Nov 7. Environ Sci Pollut Res Int. 2023. PMID: 37934407 Free PMC article.

8

150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility.

Wu Y, Goleva SB, Breidenbach LB, Kim M, MacGregor S, Gandal MJ, Davis LK, Wray NR. Wu Y, et al. Among authors: breidenbach lb. Cell Genom. 2023 Jun 5;3(7):100326. doi: 10.1016/j.xgen.2023.100326. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492107 Free PMC article.

9

Novel Bruton's Tyrosine Kinase (BTK) Substrates for Time-Resolved Luminescence Assays.

Widstrom NE, Perez M, Pratt ED, Heier JL, Blankenhorn JF, Breidenbach L, Peterson H, Parker LL. Widstrom NE, et al. Among authors: breidenbach l. ACS Chem Biol. 2022 Jun 17;17(6):1328-1333. doi: 10.1021/acschembio.2c00106. Epub 2022 Jun 2. ACS Chem Biol. 2022. PMID: 35653784 Free PMC article.

10

Nonsynonymous single-nucleotide polymorphisms in the G6PC2 gene affect protein expression, enzyme activity, and fasting blood glucose.

Overway EM, Bosma KJ, Claxton DP, Oeser JK, Singh K, Breidenbach LB, Mchaourab HS, Davis LK, O'Brien RM. Overway EM, et al. Among authors: breidenbach lb. J Biol Chem. 2022 Feb;298(2):101534. doi: 10.1016/j.jbc.2021.101534. Epub 2021 Dec 23. J Biol Chem. 2022. PMID: 34954144 Free PMC article.

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