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Inhibition of chloroplast translation as a new target for herbicides.
Sukhoverkov KV, Breese KJ, Debowski AW, Murcha MW, Stubbs KA, Mylne JS. Sukhoverkov KV, et al. Among authors: breese kj. RSC Chem Biol. 2021 Nov 10;3(1):37-43. doi: 10.1039/d1cb00192b. eCollection 2022 Jan 5. RSC Chem Biol. 2021. PMID: 35128407 Free PMC article.
Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter.
Rodrigo MKD, Saiganesh A, Hayes AJ, Wilson AM, Anstey J, Pickering JL, Iwasaki J, Hillas J, Winslow S, Woodman T, Nitschke P, Lacey JA, Breese KJ, van der Linden MPG, Giffard PM, Tong SYC, Gray N, Stubbs KA, Carapetis JR, Bowen AC, Davies MR, Barnett TC. Rodrigo MKD, et al. Among authors: breese kj. Nat Commun. 2022 Nov 30;13(1):6557. doi: 10.1038/s41467-022-34243-3. Nat Commun. 2022. PMID: 36450721 Free PMC article.
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1.
Braillard S, Keenan M, Breese KJ, Heppell J, Abbott M, Islam R, Shackleford DM, Katneni K, Crighton E, Chen G, Patil R, Lee G, White KL, Carvalho S, Wall RJ, Chemi G, Zuccotto F, González S, Marco M, Deakyne J, Standing D, Brunori G, Lyon JJ, Castañeda-Casado P, Camino I, Martinez Martinez MS, Zulfiqar B, Avery VM, Feijens PB, Van Pelt N, Matheeussen A, Hendrickx S, Maes L, Caljon G, Yardley V, Wyllie S, Charman SA, Chatelain E. Braillard S, et al. Among authors: breese kj. Sci Transl Med. 2023 Dec 13;15(726):eadh9902. doi: 10.1126/scitranslmed.adh9902. Epub 2023 Dec 13. Sci Transl Med. 2023. PMID: 38091406 Free PMC article.