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Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys.
Bellot M, Luetjens CM, Bagger M, Horvath C, Sutter E, DeLise A, Brees D, Carballido JM, Pingili R, Ramanathan K, Kieseier BC, Hellwig K. Bellot M, et al. Among authors: brees d. Reprod Toxicol. 2022 Mar;108:28-34. doi: 10.1016/j.reprotox.2021.12.006. Epub 2021 Dec 21. Reprod Toxicol. 2022. PMID: 34942355 Free article.
Safety differentiation: emerging competitive edge in drug development.
Uteng M, Urban L, Brees D, Muller PY, Kullak-Ublick GA, Bouchard P, Tougas G, Chibout SD. Uteng M, et al. Among authors: brees d. Drug Discov Today. 2019 Jan;24(1):285-292. doi: 10.1016/j.drudis.2018.09.009. Epub 2018 Sep 19. Drug Discov Today. 2019. PMID: 30244081 Free article. Review.
Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity.
Wolf B, Piksa M, Beley I, Patoux A, Besson T, Cordier V, Voedisch B, Schindler P, Stöllner D, Perrot L, von Gunten S, Brees D, Kammüller M. Wolf B, et al. Among authors: brees d. Immunology. 2022 Jul;166(3):380-407. doi: 10.1111/imm.13481. Epub 2022 May 4. Immunology. 2022. PMID: 35416297 Free article.
Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization.
Segueni N, Tritto E, Bourigault ML, Rose S, Erard F, Le Bert M, Jacobs M, Di Padova F, Stiehl DP, Moulin P, Brees D, Chibout SD, Ryffel B, Kammüller M, Quesniaux VF. Segueni N, et al. Among authors: brees d. Sci Rep. 2016 Nov 17;6:36923. doi: 10.1038/srep36923. Sci Rep. 2016. PMID: 27853279 Free PMC article.
Investigative safety science as a competitive advantage for Pharma.
Moggs J, Moulin P, Pognan F, Brees D, Leonard M, Busch S, Cordier A, Heard DJ, Kammüller M, Merz M, Bouchard P, Chibout SD. Moggs J, et al. Among authors: brees d. Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1071-82. doi: 10.1517/17425255.2012.693914. Epub 2012 Jul 7. Expert Opin Drug Metab Toxicol. 2012. PMID: 22769724 Review.
44 results