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Protein modification with ISG15 blocks coxsackievirus pathology by antiviral and metabolic reprogramming.
Kespohl M, Bredow C, Klingel K, Voß M, Paeschke A, Zickler M, Poller W, Kaya Z, Eckstein J, Fechner H, Spranger J, Fähling M, Wirth EK, Radoshevich L, Thery F, Impens F, Berndt N, Knobeloch KP, Beling A. Kespohl M, et al. Among authors: bredow c. Sci Adv. 2020 Mar 11;6(11):eaay1109. doi: 10.1126/sciadv.aay1109. eCollection 2020 Mar. Sci Adv. 2020. PMID: 32195343 Free PMC article.
Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.
Thery F, Martina L, Asselman C, Zhang Y, Vessely M, Repo H, Sedeyn K, Moschonas GD, Bredow C, Teo QW, Zhang J, Leandro K, Eggermont D, De Sutter D, Boucher K, Hochepied T, Festjens N, Callewaert N, Saelens X, Dermaut B, Knobeloch KP, Beling A, Sanyal S, Radoshevich L, Eyckerman S, Impens F. Thery F, et al. Among authors: bredow c. Nat Commun. 2021 Oct 1;12(1):5772. doi: 10.1038/s41467-021-26061-w. Nat Commun. 2021. PMID: 34599178 Free PMC article.
TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice.
Kespohl M, Goetzke CC, Althof N, Bredow C, Kelm N, Pinkert S, Bukur T, Bukur V, Grunz K, Kaur D, Heuser A, Mülleder M, Sauter M, Klingel K, Weiler H, Berndt N, Gaida MM, Ruf W, Beling A. Kespohl M, et al. Among authors: bredow c. Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):843-865. doi: 10.1161/ATVBAHA.123.320157. Epub 2024 Feb 22. Arterioscler Thromb Vasc Biol. 2024. PMID: 38385286 Free article.
ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.
Bredow C, Thery F, Wirth EK, Ochs S, Kespohl M, Kleinau G, Kelm N, Gimber N, Schmoranzer J, Voss M, Klingel K, Spranger J, Renko K, Ralser M, Mülleder M, Heuser A, Knobeloch KP, Scheerer P, Kirwan J, Brüning U, Berndt N, Impens F, Beling A. Bredow C, et al. Cardiovasc Res. 2024 May 7;120(6):644-657. doi: 10.1093/cvr/cvae026. Cardiovasc Res. 2024. PMID: 38309955 Free PMC article.
Registered Replication Report: Study 1 From Finkel, Rusbult, Kumashiro, & Hannon (2002).
Cheung I, Campbell L, LeBel EP, Ackerman RA, Aykutog˘lu B, Bahník Š, Bowen JD, Bredow CA, Bromberg C, Caprariello PA, Carcedo RJ, Carson KJ, Cobb RJ, Collins NL, Corretti CA, DiDonato TE, Ellithorpe C, Fernández-Rouco N, Fuglestad PT, Goldberg RM, Golom FD, Gündog˘du-Aktürk E, Hoplock LB, Houdek P, Kane HS, Kim JS, Kraus S, Leone CT, Li NP, Logan JM, Millman RD, Morry MM, Pink JC, Ritchey T, Root Luna LM, Sinclair HC, Stinson DA, Sucharyna TA, Tidwell ND, Uysal A, Vranka M, Winczewski LA, Yong JC. Cheung I, et al. Among authors: bredow ca. Perspect Psychol Sci. 2016 Sep;11(5):750-764. doi: 10.1177/1745691616664694. Perspect Psychol Sci. 2016. PMID: 27694468
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