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The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation.
Totland MZ, Knudsen LM, Rasmussen NL, Omori Y, Sørensen V, Elster VCW, Stenersen JM, Larsen M, Jensen CL, Zickfeldt Lade AA, Bruusgaard E, Basing S, Kryeziu K, Brech A, Aasen T, Lothe RA, Leithe E. Totland MZ, et al. Among authors: brech a. Cell Mol Life Sci. 2024 Apr 10;81(1):171. doi: 10.1007/s00018-024-05165-8. Cell Mol Life Sci. 2024. PMID: 38597989 Free PMC article.
Modulation of lytic molecules restrain serial killing in γδ T lymphocytes.
Sandoz PA, Kuhnigk K, Szabo EK, Thunberg S, Erikson E, Sandström N, Verron Q, Brech A, Watzl C, Wagner AK, Alici E, Malmberg KJ, Uhlin M, Önfelt B. Sandoz PA, et al. Among authors: brech a. Nat Commun. 2023 Sep 27;14(1):6035. doi: 10.1038/s41467-023-41634-7. Nat Commun. 2023. PMID: 37758698 Free PMC article.
Endocytic trafficking of connexins in cancer pathogenesis.
Totland MZ, Omori Y, Sørensen V, Kryeziu K, Aasen T, Brech A, Leithe E. Totland MZ, et al. Among authors: brech a. Biochim Biophys Acta Mol Basis Dis. 2023 Oct;1869(7):166812. doi: 10.1016/j.bbadis.2023.166812. Epub 2023 Jul 16. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 37454772 Free article. Review.
siRNA screening reveals that SNAP29 contributes to exosome release.
Hessvik NP, Sagini K, Romero S, Ramirez-Garrastacho M, Rodriguez M, Tutturen AEV, Kvalvaag A, Stang E, Brech A, Sandvig K, Llorente A. Hessvik NP, et al. Among authors: brech a. Cell Mol Life Sci. 2023 Jun 7;80(7):177. doi: 10.1007/s00018-023-04822-8. Cell Mol Life Sci. 2023. PMID: 37285022 Free PMC article.
BIN1, Myotubularin, and Dynamin-2 Coordinate T-Tubule Growth in Cardiomyocytes.
Perdreau-Dahl H, Lipsett DB, Frisk M, Kermani F, Carlson CR, Brech A, Shen X, Bergan-Dahl A, Hou Y, Tuomainen T, Tavi P, Jones PP, Lunde M, Wasserstrom JA, Laporte J, Ullrich ND, Christensen G, Morth JP, Louch WE. Perdreau-Dahl H, et al. Among authors: brech a. Circ Res. 2023 May 26;132(11):e188-e205. doi: 10.1161/CIRCRESAHA.122.321732. Epub 2023 May 4. Circ Res. 2023. PMID: 37139790 Free article.
129 results